Results 41 to 50 of about 137,378 (339)

Shining new light on mammalian diving physiology using wearable near-infrared spectroscopy [PDF]

, 2019
Investigation of marine mammal dive-by-dive blood distribution and oxygenation has been limited by a lack of non-invasive technology for use in freely diving animals.
Balfour, Steve, Bennett, Kimberley A., Bivins, Matt, Bronkhorst, Mathijs, Colier, Willy, Hall, Ailsa J., McKnight, J. Chris, Milne, Ryan, Moss, Simon E. W., Russell, Debbie J. F., Thompson, Dave   +10 more
core   +4 more sources

Hyperglycaemia does not increase perfusion deficits after focal cerebral ischaemia in male Wistar rats [PDF]

, 2018
Background: Hyperglycaemia is associated with a worse outcome in acute ischaemic stroke patients; yet the pathophysiological mechanisms of hyperglycaemia-induced damage are poorly understood.
Dewar, Deborah, Holmes, William M., MacDonald, Kathleen, Macrae, I. Mhairi, Muir, Keith W., Thow, Lisa A.   +5 more
core   +1 more source

Practical and comprehensive guidelines for bedside cerebral hemometabolic multitherapeutic optimization [PDF]

Arquivos de Neuro-Psiquiatria, 2002
In recent years, noncomprehensive "guidelines" were proposed for the management of severe acute brain injuries, focusing strictly on two approaches: 1) to maintain cerebral perfusion pressure anywhere above 70 mm Hg; and 2) to maintain arterial carbon ...
Julio Cruz
doaj   +1 more source

The future of ischemic stroke: flow from prehospital neuroprotection to definitive reperfusion. [PDF]

, 2014
Recent advances in ischemic stroke enable a seamless transition of the patient flow from the prehospital setting to definitive reperfusion, without the arbitrary separation of therapeutic phases of ischemia based on time alone.
Ip, Hing Lung, Liebeskind, David S
core   +1 more source

Effect of Hyperosmolar Solutions on Cerebral Oxygenation and Metabolism

Общая реаниматология, 2008
Objective: to assess the time course of changes in the parameters of cerebral oxygenation and metabolism in the correction of intracranial hypertension with hyperosmolar solutions. Material and methods.
S. S. Petrikov, V. V. Krylov, A. A. Solodov, Yu. V. Titova, Kh. T. Guseinova, L. T. Khamidova   +5 more
doaj   +1 more source

Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra [PDF]

, 2008
We describe a novel magnetic resonance imaging technique for detecting metabolism indirectly through changes in oxyhemoglobin:deoxyhemoglobin ratios and T2* signal change during ‘oxygen challenge’ (OC, 5 mins 100% O2). During OC, T2* increase reflects O2
Barrie Condon, Brierley JB, Celestine Santosh, Christopher McCabe, David Brennan, David I Graham, Donald M Hadley, Haacke EM, I Mhairi Macrae, Keith W Muir, Law R, Lindsay Gallagher, Scremin OU, William M Holmes, Willy Gsell   +14 more
core   +1 more source

Inter-individual Relationships between Sympathetic Arterial Baroreflex Function and Cerebral Perfusion Control in Healthy Males

Frontiers in Neuroscience, 2017
Maintenance of adequate cerebral perfusion during normal physiological challenges requires integration between cerebral blood flow (CBF) and systemic blood pressure control mechanisms. Previous studies have shown that cardiac baroreflex sensitivity (BRS)
Trevor Witter, Yu-Chieh Tzeng, Terry O'Donnell, Jessica Kusel, Bridget Walker, Mary Berry, Chloe E. Taylor, Chloe E. Taylor   +7 more
doaj   +1 more source

Depolarization time and extracellular glutamate levels aggravate ultraearly brain injury after subarachnoid hemorrhage

Scientific Reports, 2022
Early brain injury after aneurysmal subarachnoid hemorrhage (SAH) worsens the neurological outcome. We hypothesize that a longer duration of depolarization and excessive release of glutamate aggravate neurological outcomes after SAH, and that brain ...
Satoshi Murai, Tomohito Hishikawa, Yoshimasa Takeda, Yasuko Okura, Miki Fushimi, Hirokazu Kawase, Yu Takahashi, Naoya Kidani, Jun Haruma, Masafumi Hiramatsu, Kenji Sugiu, Hiroshi Morimatsu, Isao Date   +12 more
doaj   +1 more source

Continuous Determination of the Optimal Bispectral Index Value Based on Cerebrovascular Reactivity in Moderate/Severe Traumatic Brain Injury: A Retrospective Observational Cohort Study of a Novel Individualized Sedation Target

Critical Care Explorations, 2022
BACKGROUND:. We have sought to develop methodology for deriving optimal bispectral index (BIS) values (BISopt) for patients with moderate/severe traumatic brain injury, using continuous monitoring of cerebrovascular reactivity and bispectral ...
Logan Froese, BSc, Alwyn Gomez, BSc, MD, Amanjyot Singh Sainbhi, BSc, Carleen Batson, BSc, MD, Kevin Stein, BSc, Arsalan Alizadeh, MD, PhD, Asher A. Mendelson, BSc, MD, PhD, FRCPC, Frederick A. Zeiler, BSc, MD, PhD, CIP, FRCSC   +7 more
doaj   +1 more source

Influence of 100% and 40% oxygen on penumbral blood flow, oxygen level, and T2*-weighted MRI in a rat stroke model [PDF]

, 2011
Accurate imaging of the ischemic penumbra is a prerequisite for acute clinical stroke research. T2* magnetic resonance imaging (MRI) combined with an oxygen challenge (OC) is being developed to detect penumbra based on changes in blood deoxyhemoglobin ...
Baskerville, Tracey, Deuchar, Graeme A., Holmes, William M., Macrae, I. Mhairi, McCabe, Chris, Robertson, Craig A., Santosh, Celestine   +6 more
core   +1 more source