Results 51 to 60 of about 259,881 (379)

Hyperglycaemia does not increase perfusion deficits after focal cerebral ischaemia in male Wistar rats [PDF]

, 2018
Background: Hyperglycaemia is associated with a worse outcome in acute ischaemic stroke patients; yet the pathophysiological mechanisms of hyperglycaemia-induced damage are poorly understood.
Dewar, Deborah, Holmes, William M., MacDonald, Kathleen, Macrae, I. Mhairi, Muir, Keith W., Thow, Lisa A.   +5 more
core   +1 more source

Practical and comprehensive guidelines for bedside cerebral hemometabolic multitherapeutic optimization [PDF]

Arquivos de Neuro-Psiquiatria, 2002
In recent years, noncomprehensive "guidelines" were proposed for the management of severe acute brain injuries, focusing strictly on two approaches: 1) to maintain cerebral perfusion pressure anywhere above 70 mm Hg; and 2) to maintain arterial carbon ...
Julio Cruz
doaj   +1 more source

Cerebral Perfusion Pressure Insults and Associations with Outcome in Adult Traumatic Brain Injury

Journal of Neurotrauma, 2017
The definition of cerebral perfusion pressure (CPP) secondary insults in severe traumatic brain injury remains unclear. The purpose of the present study is to visualize the association of intensity and duration of episodes below or above CPP thresholds ...
F. Güiza, G. Meyfroidt, I. Piper, G. Citerio, I. Chambers, P. Enblad, P. Nillson, B. Feyen, P. Jorens, A. Maas, M. Schuhmann, R. Donald, L. Moss, G. Van den Berghe, B. Depreitere   +14 more
semanticscholar   +1 more source

Effect of Hyperosmolar Solutions on Cerebral Oxygenation and Metabolism

Общая реаниматология, 2008
Objective: to assess the time course of changes in the parameters of cerebral oxygenation and metabolism in the correction of intracranial hypertension with hyperosmolar solutions. Material and methods.
S. S. Petrikov, V. V. Krylov, A. A. Solodov, Yu. V. Titova, Kh. T. Guseinova, L. T. Khamidova   +5 more
doaj   +1 more source

Evaluation of the Appropriate Root Pressure for Maintaining Heartbeat during an Aortic Cross-clamp for Primary Repair of the Aortic Arch in Premature Infants with Associated Cardiac Anomalies [PDF]

, 2010
We developed a new cardiopulmonary bypass (CPB) method to minimize myocardial damage during aortic arch reconstruction. In this method, coronary flow and heartbeat were stabilized by maintaining the aortic root pressure with an adjusted preload of the ...
Honjo, Osami, Ishino, Kozo, Kotani, Yasuhiro, Osaki, Satoru, Sano, Shunji, Suezawa, Takanori   +5 more
core   +1 more source

Inter-individual Relationships between Sympathetic Arterial Baroreflex Function and Cerebral Perfusion Control in Healthy Males

Frontiers in Neuroscience, 2017
Maintenance of adequate cerebral perfusion during normal physiological challenges requires integration between cerebral blood flow (CBF) and systemic blood pressure control mechanisms. Previous studies have shown that cardiac baroreflex sensitivity (BRS)
Trevor Witter, Yu-Chieh Tzeng, Terry O'Donnell, Jessica Kusel, Bridget Walker, Mary Berry, Chloe E. Taylor, Chloe E. Taylor   +7 more
doaj   +1 more source

Depolarization time and extracellular glutamate levels aggravate ultraearly brain injury after subarachnoid hemorrhage

Scientific Reports, 2022
Early brain injury after aneurysmal subarachnoid hemorrhage (SAH) worsens the neurological outcome. We hypothesize that a longer duration of depolarization and excessive release of glutamate aggravate neurological outcomes after SAH, and that brain ...
Satoshi Murai, Tomohito Hishikawa, Yoshimasa Takeda, Yasuko Okura, Miki Fushimi, Hirokazu Kawase, Yu Takahashi, Naoya Kidani, Jun Haruma, Masafumi Hiramatsu, Kenji Sugiu, Hiroshi Morimatsu, Isao Date   +12 more
doaj   +1 more source

Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra [PDF]

, 2008
We describe a novel magnetic resonance imaging technique for detecting metabolism indirectly through changes in oxyhemoglobin:deoxyhemoglobin ratios and T2* signal change during ‘oxygen challenge’ (OC, 5 mins 100% O2). During OC, T2* increase reflects O2
Barrie Condon, Brierley JB, Celestine Santosh, Christopher McCabe, David Brennan, David I Graham, Donald M Hadley, Haacke EM, I Mhairi Macrae, Keith W Muir, Law R, Lindsay Gallagher, Scremin OU, William M Holmes, Willy Gsell   +14 more
core   +1 more source

Shining new light on mammalian diving physiology using wearable near-infrared spectroscopy [PDF]

, 2019
Investigation of marine mammal dive-by-dive blood distribution and oxygenation has been limited by a lack of non-invasive technology for use in freely diving animals.
Balfour, Steve, Bennett, Kimberley A., Bivins, Matt, Bronkhorst, Mathijs, Colier, Willy, Hall, Ailsa J., McKnight, J. Chris, Milne, Ryan, Moss, Simon E. W., Russell, Debbie J. F., Thompson, Dave   +10 more
core   +4 more sources

Continuous Determination of the Optimal Bispectral Index Value Based on Cerebrovascular Reactivity in Moderate/Severe Traumatic Brain Injury: A Retrospective Observational Cohort Study of a Novel Individualized Sedation Target

Critical Care Explorations, 2022
BACKGROUND:. We have sought to develop methodology for deriving optimal bispectral index (BIS) values (BISopt) for patients with moderate/severe traumatic brain injury, using continuous monitoring of cerebrovascular reactivity and bispectral ...
Logan Froese, BSc, Alwyn Gomez, BSc, MD, Amanjyot Singh Sainbhi, BSc, Carleen Batson, BSc, MD, Kevin Stein, BSc, Arsalan Alizadeh, MD, PhD, Asher A. Mendelson, BSc, MD, PhD, FRCPC, Frederick A. Zeiler, BSc, MD, PhD, CIP, FRCSC   +7 more
doaj   +1 more source