Results 51 to 60 of about 43,286 (202)

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

Med Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang, Yuying Mo, Zhishan Ling, Yuting Zeng, Qi Zhang, Shuqi Zheng, Shuyang Wen, Yupeng Xiao, Siying Long, Tingting Yang, Qianru Li, Wenjie Shi, Guozhi Huang, Qing Zeng   +13 more
wiley   +1 more source

Screening of postoperative cerebral hyperperfusion syndrome in moyamoya disease: a three-dimensional pulsed arterial-spin labeling magnetic resonance imaging approach

Frontiers in Neuroscience, 2023
IntroductionMoyamoya disease (MMD) is associated with a risk of postoperative cerebral hyperperfusion syndrome (CHS) after revascularization surgery. This study aimed to explore the feasibility of using three-dimensional pulsed arterial spin labeling (3D
Feng Gao, Jianhua Cong, Yu Duan, Wei Zhao, Zhenfang Zhu, Yu Zheng, Liang Jin, Ming Ji, Ming Li   +8 more
doaj   +1 more source

Inflammatory Cytokines as Early Predictors of Weaning Failure From Extracorporeal Life Support

Artificial Organs, EarlyView.
Levels of IL‐8 and IL‐6 and their dynamics are reliable early predictors of ECLS weaning failure. ABSTRACT Background Weaning from extracorporeal life support (ECLS) in patients with refractory shock still remains a complex decision. Despite considerable advances in ECLS management, reliable biomarkers to predict weaning success are still not available.
Kostiantyn Kozakov, Alois Philipp, Maik Foltan, Anton Heller, Dzmitry Turtsevich, Christian Schach, Peter‐Paul Ellmauer, Walter Petermichl, Bernhard Flörchinger, Christof Schmid, Simon Schopka, Zdenek Provaznik   +11 more
wiley   +1 more source

Pseudo-continuous and territorial arterial spin labeling MRI for assessment of cerebral perfusion in moyamoya disease after revascularization: A comparative study with digital subtraction angiography

Heliyon
Purpose: To evaluate if pseudo-continuous arterial spin labeling (pcASL) and territorial ASL (tASL) can assess cerebral perfusion post-revascularization in Moyamoya disease and compare with digital subtraction angiography (DSA) outcomes.
Juan Li, Qinghu Meng, Ling Huang, Dmytro Pylypenko, Hai Zhong   +4 more
doaj   +1 more source

Vascularised Brain Organoids: Engineering Strategies and Neurobiological Applications

Cell Proliferation, EarlyView.
This review highlights emerging strategies to engineer vascularized brain organoids—including endothelial co‐culture, genetic induction, perfusion systems, and in vivo transplantation—and their applications in modelling neurovascular diseases, evaluating BBB drug delivery, and advancing regenerative medicine.
Yeajin Song, Hyejin Jo, Seokchan Jeong, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Evolution of cerebral revascularization techniques

Neurosurgical Focus, 2008
✓As a leading cause of death and disability in patients across the world, stroke is a problem that plagues both neurosurgeons and neurologists alike. Whether a result of atherosclerosis, moyamoya disease, or a complication in the treatment of a complex intracranial aneurysm, cerebrovascular occlusion can have devastating effects on patients. For nearly
R Webster, Crowley, Ricky, Medel, Aaron S, Dumont   +2 more
openaire   +2 more sources

The clinical and physiological profiles of kissing stents in endovascular reconstruction of aortoiliac occlusive disease

Experimental Physiology, EarlyView.
Abstract Aortoiliac occlusive disease affecting the abdominal aorta and iliac arteries is conventionally treated with open surgical repair and is the mainstay of treatment. Endovascular techniques have become a less invasive alternative, especially for high‐risk patients.
Christopher J. Goulden, Matti Jubouri, Eka Narayan, Sakshi Roy, Fatima Kayali, Wael I. Awad, Damian M. Bailey, Ian M. Williams, Mohamad Bashir   +8 more
wiley   +1 more source

Risk Factors for Incident Carotid Artery Revascularization among Older Adults: The Cardiovascular Health Study

Cerebrovascular Diseases Extra, 2016
Background: Population-based risk factors for carotid artery revascularization are not known. We investigated the association between demographic and clinical characteristics and incident carotid artery revascularization in a cohort of older adults ...
Parveen K. Garg, Willam J.H. Koh, Joseph A. Delaney, Ethan A. Halm, Calvin H. Hirsch, William T. Longstreth Jr., Kenneth J. Mukamal, Anna Kucharska-Newton, Joseph F. Polak, Lesley Curtis   +9 more
doaj   +1 more source

Bilateral dynamic cerebral autoregulation assessment during endovascular treatment in large‐vessel occlusion stroke

Experimental Physiology, EarlyView.
Abstract Recanalization by endovascular treatment (EVT) is effective in acute ischaemic stroke caused by large‐vessel occlusion. Better understanding of the pathophysiology could possibly identify targets for improving peri‐procedural management and thereby patient outcome.
Adam Vittrup Heiberg, Troels Gil Lukassen, Thomas Clement Truelsen, Henrik Gutte Borgwardt, Goetz Benndorf, Christine Sølling, Henrik Winther Schytz, Klaus Hansen, Kirsten Møller, Helle Klingenberg Iversen   +9 more
wiley   +1 more source

Paradoxical symptomatic cerebral blood flow decreases after combined revascularization surgery for patients with pediatric moyamoya disease: illustrative case [PDF]

, 2022
Yoshio Araki, Kinya Yokoyama, Kenji U�da, Fumiaki Kanamori, Michihiro Kurimoto, Yoshiki Shiba, Takashi Mamiya, Kai Takayanagi, Kazuki Ishii, Masahiro Nishihori, Kazuhito Takeuchi, Kuniaki Tanahashi, Yuichi Nagata, Yusuke Nishimura, Sho Okamoto, Masaki Sumitomo, Takashi Izumi, Ryuta Saito   +17 more
openalex   +1 more source