Results 81 to 90 of about 990,878 (250)

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

Neuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher, Anna F. Dominiczak, Luis M. Garcia‐Segura, Nobuhiro Harada, J. B. Hutchison, James M. Mullin, Delyth Graham, Peter O'Shaughnessy, Hilary Victoria O. Carswell   +8 more
wiley   +1 more source

Comprehensive Evaluation of Cerebral Hemodynamics and Oxygen Metabolism in Revascularization of Asymptomatic High-Grade Carotid Stenosis

, 2021
Introduction!#!Revascularization procedures in carotid artery stenosis have shown a positive effect in the restoration of cerebral oxygen metabolism as assessed by T2' (T2 prime) imaging as well as capillary homeostasis by measurement of capillary ...
Sedlacik, Jan, Schröder, Julian, Heinze, Marlene, Østergaard, Leif, Thomalla, Götz, Gerloff, Christian, Cheng, Bastian, Crespo Pimentel, Bernardo, Fiehler, Jens   +8 more
core   +1 more source

Pseudo-continuous and territorial arterial spin labeling MRI for assessment of cerebral perfusion in moyamoya disease after revascularization: A comparative study with digital subtraction angiography

Heliyon
Purpose: To evaluate if pseudo-continuous arterial spin labeling (pcASL) and territorial ASL (tASL) can assess cerebral perfusion post-revascularization in Moyamoya disease and compare with digital subtraction angiography (DSA) outcomes.
Juan Li, Qinghu Meng, Ling Huang, Dmytro Pylypenko, Hai Zhong   +4 more
doaj   +1 more source

Screening of postoperative cerebral hyperperfusion syndrome in moyamoya disease: a three-dimensional pulsed arterial-spin labeling magnetic resonance imaging approach

Frontiers in Neuroscience, 2023
IntroductionMoyamoya disease (MMD) is associated with a risk of postoperative cerebral hyperperfusion syndrome (CHS) after revascularization surgery. This study aimed to explore the feasibility of using three-dimensional pulsed arterial spin labeling (3D
Feng Gao, Jianhua Cong, Yu Duan, Wei Zhao, Zhenfang Zhu, Yu Zheng, Liang Jin, Ming Ji, Ming Li   +8 more
doaj   +1 more source

A catastrophic confluence: Concurrent subarachnoid haemorrhage and acute mesenteric ischaemia

Surgical Practice, EarlyView.
Abstract Background Acute mesenteric ischaemia (AMI) and subarachnoid haemorrhage (SAH) are life‐threatening emergencies with diametrically opposed treatment requirements regarding anticoagulation. This report describes a rare, complex case where both conditions occurred simultaneously, creating a significant therapeutic dilemma. Case presentation A 64‐
Ip Ki Fung Shavonne
wiley   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Superficial Temporal Artery-To-Middle Cerebral Artery Bypass Grafting for Cerebral Revascularization

, 2004
SUPERFICIAL TEMPORAL ARTERY-to-middle cerebral artery bypass procedures are an important toot in the armamentarium of cerebrovascular surgeons for the treatment of carotid occlusion and revascularization for complex aneurysms and brain tumors.
Wanebo, John E., Spetzler, Robert F., Zabramski, Joseph M.   +2 more
core   +1 more source

Prediabetes, Malignant Ventricular Hypertrophy and Stroke: The SPRINT Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Prediabetes and left ventricular hypertrophy (LVH) are common risk factors in adults with hypertension. Whether their coexistence, particularly in the presence of subclinical myocardial injury or stress (malignant LVH), confers a heightened stroke risk is unknown.
Arnaud D. Kaze, Stephen P. Juraschek, Jordana B. Cohen, Siddharth Singh, Chiadi E. Ndumele, Christie M. Ballantyne, Jarrett D. Berry, Justin B. Echouffo‐Tcheugui   +7 more
wiley   +1 more source

Risk Factors for Incident Carotid Artery Revascularization among Older Adults: The Cardiovascular Health Study

Cerebrovascular Diseases Extra, 2016
Background: Population-based risk factors for carotid artery revascularization are not known. We investigated the association between demographic and clinical characteristics and incident carotid artery revascularization in a cohort of older adults ...
Parveen K. Garg, Willam J.H. Koh, Joseph A. Delaney, Ethan A. Halm, Calvin H. Hirsch, William T. Longstreth Jr., Kenneth J. Mukamal, Anna Kucharska-Newton, Joseph F. Polak, Lesley Curtis   +9 more
doaj   +1 more source

GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano, Line L. Haurum, Christine R. Schwarz, Francesca Porcellati, Andreas Andersen   +4 more
wiley   +1 more source