Results 111 to 120 of about 435,514 (353)

Acute Paraplegia with Cognitive Alterations After Bilateral Infarcts in Cerebral Small Vessel Disease [PDF]

, 2017
Cerebral small vessel disease (SVD) affects the small arteries, arterioles, venules and capillaries in the brain and can be identified clinically and/or radiologically.
Forteza, Francisco Javier Ros
core   +2 more sources

Occurrence, Risk Factors, and Prognosis of Acute Cerebral Microinfarcts in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic cerebral small vessel disease in adults. This study investigates the occurrence, risk factors, and prognosis of acute cerebral microinfarcts (ACMIs) in patients with CADASIL.
Xuejiao Men, Hui Li, Zhuoxin Guo, Bin Qin, Hengfang Ruan, Ruipeng Cai, Bingjun Zhang, Aimin Wu, Lei Wei, Yongqiang Dai, Haiyan Li, Zhengqi Lu   +11 more
wiley   +1 more source

Processing efficiency in pediatric cancer survivors: A review and operationalization for outcomes research and clinical utility

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Objective Childhood cancer and cancer‐related treatments disrupt brain development and maturation, placing survivors at risk for cognitive late effects. Given that assessment tools vary widely across researchers and clinicians, it has been daunting to identify distinct patterns in outcomes across diverse cancer types and to implement ...
Julie A. Trapani, Donna L. Murdaugh
wiley   +1 more source

Cerebrovascular morphology in aging and disease -- imaging biomarkers for ischemic stroke and Alzheimers disease [PDF]

arXiv, 2022
Background and Purpose: Altered brain vasculature is a key phenomenon in several neurologic disorders. This paper presents a quantitative assessment of vascular morphology in healthy and diseased adults including changes during aging and the anatomical variations in the Circle of Willis (CoW).
arxiv  

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Simulation‐based team‐training in acute stroke: Is it safe to speed up?

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background In acute ischemic stroke (AIS), rapid treatment with intravenous thrombolysis (IVT) is crucial for good clinical outcome. Weekly simulation‐based team‐training of the stroke treatment team was implemented, resulting in faster treatment times.
Liv Jorunn Høllesli, Soffien Chadli Ajmi, Martin W. Kurz, Thomas Bailey Tysland, Morten Hagir, Ingvild Dalen, Sigrun Anna Qvindesland, Hege Ersdal, Kathinka D. Kurz   +8 more
wiley   +1 more source

Physics-informed neural networks for improving cerebral hemodynamics predictions [PDF]

arXiv, 2021
Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with fast computational fluid dynamics (CFD) simulations to generate physically consistent and high spatiotemporal ...
arxiv  

Neuroimaging of Cerebral Small Vessel Disease

Brain Pathology, 2014
Neuroimaging of cerebral small vessel vascular disease is often nonspecific and the diagnosis is challenging; clinical and family history is pivotal in interpreting neuroimaging findings. Hereditary small vessel diseases have recently gained significant interest, and MRI is a sensitive tool to detect white matter abnormality.
openaire   +4 more sources

Clinical relevance of cerebral small vessel diseases in cognitive impairment, neurodegeneration and stroke [PDF]

, 2019
Cerebral small vessel diseases are common age-related processes associated with two important and highly prevalent clinical syndromes: stroke and dementia.
Banerjee, Gargi
core  

Common NOTCH3 Variants and Cerebral Small-Vessel Disease. [PDF]

, 2015
BACKGROUND AND PURPOSE: The most common monogenic cause of cerebral small-vessel disease is cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, caused by NOTCH3 gene mutations.
Adib-Samii, Poneh, Bevan, Steve, Boncoraglio, Giorgio, Dichgans, Martin, Hassan, Ahamad, Levi, Christopher, Markus, Hugh S, Meschia, James, Rosand, Jonathan, Rost, Natalia S, Rothwell, Peter M, Rutten-Jacobs, Loes CA, Sudlow, Cathie, Thijs, Vincent, Traylor, Matthew   +14 more
core   +2 more sources