Results 241 to 250 of about 198,856 (347)

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

Lipids, EarlyView.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao, Nuan Wang, Di Shi, Hao Zhou, Dan Chen, Guofang Chen   +5 more
wiley   +1 more source

Executive functions and processing speed in covert cerebral small vessel disease [PDF]

Hanna Jokinen, Hanna M. Laakso, Anne Arola, Teemu Paajanen, Jussi Virkkala, Teppo Särkämö, Tommi Makkonen, Iiris Kyläheiko, Heidi Heinonen, Johanna Pitkänen, Antti Korvenoja, Susanna Melkas   +11 more
openalex   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Global Research Trends and Hotspots in Cerebral Small Vessel Disease-Related Cognitive Impairment: A Bibliometric Analysis (2001-2024). [PDF]

Brain Behav
Wang K, Ji X, Li H, Wang X, Jin X, Lin Y, Wang Q, Xu H, Ye J, Cui X, Liang Y.   +10 more
europepmc   +1 more source

Light-chain split luciferase assay implicates pathological NOTCH3 thiol reactivity in inherited cerebral small vessel disease [PDF]

Naw May Pearl Cartee, Soo Jung Lee, Emily Wu, Richard Sukpraphrute, Catherine Sukpraphrute, Jeffrey H. Greenbaum, Michael M. Wang   +6 more
openalex   +1 more source

Clinical, Genetic, and Imaging Characteristics of SCA27B: Insights from a Large Dutch Cohort

Movement Disorders, EarlyView.
Abstract Background Deep intronic GAA repeat expansions in intron 1 of the FGF14 gene were identified in 2023 as cause of late‐onset cerebellar ataxia. Since then, GAA‐FGF14‐related ataxia (SCA27B) has emerged as one of the most common genetic causes of late‐onset cerebellar ataxia.
Teije H. van Prooije, Maartje Pennings, Roderick P.P.W.M. Maas, Jeroen de Vries, Corien Verschuuren‐Bemelmans, Vincent Odekerken, Sirwan K.L. Darweesh, Mark Huisman, Mayke Oosterloo, Arthur Buijink, Jaron van de Wardt, Els Vanhoutte, Tsz Hang Wong, Lisette Koens, Eva de Boer, Judith van Gaalen, Martijn Beudel, Dareia S. Roos, Jorrit I. Hoff, Thimo Cornelissen, Meyke Schouten, Thatjana Gardeichik, Erica van der Looij, Christine Klein, Joanne Trinh, Erik‐Jan Kamsteeg, Bart van de Warrenburg   +26 more
wiley   +1 more source

Correlation between cerebral small vessel disease and postural instability/gait difficulty subtype in Parkinson's disease patients. [PDF]

Front Aging Neurosci
Ge Y, Zhao W, Xu X, Qiu W, Liu P, Zhao M, Cheng Y, Xue S.   +7 more
europepmc   +1 more source

Higher Pulsatility in Cerebral Perforating Arteries in Patients With Small Vessel Disease Related Stroke, a 7T MRI Study

, 2018
Lennart J. Geurts, Jaco J.M. Zwanenburg, Catharina J.M. Klijn, Peter R. Luijten, Geert Jan Biessels   +4 more
openalex   +1 more source

Jointly Learned 3D Non‐Cartesian Sampling With Wave Encoding and Reconstruction for Neurovascular Phase Contrast MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop accelerated 3D phase contrast (PC) MRI using jointly learned wave encoding and reconstruction. Methods Pseudo‐fully sampled neurovascular 4D flow data (N = 40) and a simulation framework were used to learn phase encoding locations, wave readout parameters, and model‐based reconstruction network (MoDL) for a rapid 3D PC scan (
Chenwei Tang, Brock W. Jolicoeur, James Rice, Caroline A. Doctor, Zaynab S. Yardim, Leonardo A. Rivera‐Rivera, Laura B. Eisenmenger, Kevin M. Johnson   +7 more
wiley   +1 more source

Retinal microvascular alterations reflect cerebral small vessel disease burden in frontotemporal dementia: a multimodal OCTA-MRI Study. [PDF]

Alzheimers Res Ther
Chen Y, Kwapong WR, Chen X, Gao Y, Chu M, Zhang X, Wu L.   +6 more
europepmc   +1 more source