Results 261 to 270 of about 435,514 (353)

A multimodal MRI-based machine learning framework for classifying cognitive impairment in cerebral small vessel disease. [PDF]

Sci Rep
Lin G, Chen W, Geng Y, Peng B, Liu S, Chen M, Pang C, Chen P, Lu C, Yan Z, Xia S, Dai Y, Ji J.   +12 more
europepmc   +1 more source

Cerebrovascular reactivity differences in healthy cerebral gray and white matter

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose To quantify the speed and magnitude of cerebrovascular reactivity (CVR) metrics in hemispheric gray and white matter. Methods A standardized isoxic hypercapnic cerebrovascular stimulus was administered using an automated arterial gas targeting system while monitoring blood oxygen–level dependent MRI.
Harrison T. Levine, Julien Poublanc, Ece Su Sayin, James Duffin, Olivia Sobczyk, Joseph A. Fisher, David J. Mikulis   +6 more
wiley   +1 more source

Association between Life's Essential 8 and Cerebral Small Vessel Disease. [PDF]

Stroke Vasc Neurol
Liu D, Cai X, Yang Y, Wang S, Mei L, Jing J, Li S, Wang M, Chen Y, Meng X, Wei T, Wang Y, Wang Y, Pan Y.   +13 more
europepmc   +1 more source

Unraveling the major role of vascular (R2') contributions to R2* signal relaxation at ultra‐high‐field MRI: A comprehensive analysis with quantitative gradient recalled echo in mouse brain

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose Ultra‐high‐field (UHF) R2* relaxometry is often used for in vivo analysis of biological tissue microstructure without accounting for vascular contributions to R2* signal, that is, the BOLD signal component, and magnetic field inhomogeneities.
Joanna Im, Biao Xiang, Victoria A. Levasseur, Alexander L. Sukstanskii, James D. Quirk, Satya V. V. N. Kothapalli, Anne H. Cross, Dmitriy A. Yablonskiy   +7 more
wiley   +1 more source

Cognitive implications and associated transcriptomic signatures of distinct regional iron depositions in cerebral small vessel disease. [PDF]

Alzheimers Dement
Wang Y, Ye C, Pan R, Tang B, Li C, Liu J, Tao W, Zhang X, Yang T, Yan Y, Jiang S, Lui S, Wu B.   +12 more
europepmc   +1 more source

The role of gut microbiota‐derived metabolites in neuroinflammation

Neuroprotection, EarlyView.
Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley   +1 more source

Association of Increased Brain Iron Levels With Anxiety and Motor Dysfunction in Cerebral Small Vessel Disease. [PDF]

CNS Neurosci Ther
Sui C, Zhang Q, Gillen K, Gao Y, Zhang N, Feng M, Xin H, Liang C, Guo L, Wang Y.   +9 more
europepmc   +1 more source

History of pre‐eclampsia negatively impacts stroke severity postpartum in rats

Neuroprotection, EarlyView.
Diagrammatic representation of the effect of pre‐eclampsia on postpartum stroke severity. e7, gestational day 7; ePE, experimental pre‐eclampsia; NormP, normal pregnancy; PP, postpartum; tMCAO, transient middle cerebral artery occlusion. Made in Biorender.
Ari Kropf, Jennifer L. Anderson, Milena Esposito, Sarah M. Tremble, Marilyn J. Cipolla   +4 more
wiley   +1 more source

Imaging brain fluid dynamics and waste clearance involving perivascular spaces in cerebral small vessel disease. [PDF]

Alzheimers Dement
Solé-Guardia G, Li H, Willemse L, Lebenberg J, Jouvent E, Tuladhar AM.   +5 more
europepmc   +1 more source

European Stroke Organisation (ESO) Guideline on Cerebral Small Vessel Disease, Part 2, Lacunar Ischaemic Stroke [PDF]

Chabriat, Hugues, de Leeuw, Frank-Erik, Debette, Stépanie, Dichgans, Martin, Doubal, Fergus, Hussain, Salman, Jokinen, Hanna, Katsanos, Aristeidis H., Lindgren, Arne G, Ornello, Raffaele, Pantoni, Leonardo, Pasi, Marco, Pavlovic, Aleksandra M, Rudilosso, Salvatore, Schmidt, Reinhold, Staals, Julie, Taylor-rowan, Martin, Wardlaw, Joanna M.   +17 more
core   +1 more source