Results 271 to 280 of about 435,514 (353)

Prediction models for cognitive impairment in middle-aged patients with cerebral small vessel disease. [PDF]

Front Neurol
Zheng W, Qin X, Mu R, Yang P, Huang B, Song Z, Zhu X.   +6 more
europepmc   +1 more source

Management of Calvarial Osteoradionecrosis After Treatment of Cutaneous Malignancy: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Osteoradionecrosis (ORN) is a recognized complication of radiotherapy. However, calvarial ORN (ORNC) following treatment for cutaneous malignancies is poorly understood. Shedding light on the limited evidence to date, this study aims to summarize existing evidence and highlight the research gaps.
Siyuan Pang, Elizabeth Concannon, Martin Higgins, Katharine Drummond, Peter Gearing, Maxim Devine, Albert Tiong, Anand Ramakrishnan, Carly Fox   +8 more
wiley   +1 more source

Proteins Involved in Endothelial Function and Inflammation Are Implicated in Cerebral Small Vessel Disease. [PDF]

Stroke
Sun Z, Harshfield EL, de Leeuw FE, Burgess S, Butterworth AS, Riksen NP, Mallat Z, Markus HS.   +7 more
europepmc   +1 more source

Progress in Aptamer Research and Future Applications

ChemistryOpen, EarlyView.
This paper mainly describes the screening method of aptamer, the screening difficulties and improvement methods of small molecule aptamer, and the application and treatment of aptamer. It explores the latest progress and application of aptamers, and summarises them, thus indicating some problems that still exist in this field.
Song Liu, Xiaolu Li, Huyang Gao, Jing Chen, Hongfeng Jiang   +4 more
wiley   +1 more source

Cerebrovascular Function in Sporadic and Genetic Cerebral Small Vessel Disease. [PDF]

Ann Neurol
Stringer MS, Blair GW, Kopczak A, Kerkhofs D, Thrippleton MJ, Chappell FM, Maniega SM, Brown R, Shuler K, Hamilton I, Garcia DJ, Doubal FN, Clancy U, Sakka E, Poliakova T, Janssen E, Duering M, Ingrisch M, Staals J, Backes WH, van Oostenbrugge R, Biessels GJ, Dichgans M, Wardlaw JM, SVDs@target consortium.   +24 more
europepmc   +1 more source

Experimental Impact of Increasing Circuit Resistance in the Artificial Womb

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To determine the impact of controlled incremental changes in circuit blood flow resistance to the oxygenator on hemodynamics in the fetal lamb supported by the EXTrauterine Environment for Neonatal Development (EXTEND) system.
Haiyan Cao, Marcus G. Davey, Kathleen Young, Zhiyun Tian, Seitaro Kosaka, Maria F. Varela, Alan W. Flake, Jack Rychik   +7 more
wiley   +1 more source

Urinary Proteomics and Systems Biology Link Eight Proteins to the Higher Risk of Hypertension and Related Complications in Blacks Versus Whites

PROTEOMICS, EarlyView.
ABSTRACT Blacks are more prone to salt‐sensitive hypertension than Whites. This cross‐sectional analysis of a multi‐ethnic cohort aimed to search for proteins potentially involved in the susceptibility to salt sensitivity, hypertension, and hypertension‐related complications.
De‐Wei An, Dries S. Martens, Gontse G. Mokwatsi, Yu‐Ling Yu, Babangida S. Chori, Agnieszka Latosinska, Godsent Isiguzo, Susanne Eder, Dong‐Yan Zhang, Gert Mayer, Ruan Kruger, Jana Brguljan‐Hitij, Christian Delles, Catharina M. C. Mels, Katarzyna Stolarz‐Skrzypek, Marek Rajzer, Peter Verhamme, Aletta E. Schutte, Tim S. Nawrot, Yan Li, Harald Mischak, Augustine N. Odili, Jan A. Staessen   +22 more
wiley   +1 more source

Artesunate alleviated hippocampal neuron pyroptosis by down-regulating NLRP3 in rats with cerebral small vessel disease. [PDF]

Metab Brain Dis
Wang X, Zhong H, Kong X, Wei H, Li B.
europepmc   +1 more source

Microglial Drivers of Alzheimer's Disease Pathology: An Evolution of Diverse Participating States

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Microglia, the resident immune‐competent cells of the brain, become dysfunctional in Alzheimer's disease (AD), and their aberrant immune responses contribute to the accumulation of pathological proteins and neuronal injury. Genetic studies implicate microglia in the development of AD, prompting interest in developing immunomodulatory therapies
Madison K. Kuhn, Elizabeth A. Proctor
wiley   +1 more source