Results 291 to 300 of about 435,514 (353)

The Microbiota-Gut-Brain Axis: Key Mechanisms Driving Glymphopathy and Cerebral Small Vessel Disease. [PDF]

open access: yesLife (Basel)
Che Mohd Nassir CMN   +6 more
europepmc   +1 more source

Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age‐Related Blood–Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice

open access: yesAging Cell, EarlyView.
Senolytic therapy restores neurovascular function, blood–brain barrier integrity, and cognitive performance in aged mice by targeting endothelial senescence. Findings highlight that brain microvascular endothelial cells are highly vulnerable to aging‐induced senescence, and early intervention in middle age may be the most effective strategy to prevent ...
Boglarka Csik   +20 more
wiley   +1 more source

Systematic Review of Rare Major Adverse Cardiovascular Events Associated With the Treatment of Acne With Isotretinoin

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Acne vulgaris is a common inflammatory condition that is often treated by dermatologists with isotretinoin. Isotretinoin has a number of effects on inflammatory pathways, with clear efficacy in managing acne vulgaris. There are also well‐documented side effects of isotretinoin, including hyperlipidemia; however, the overall cardiovascular risk
Timothy L. Cowan   +3 more
wiley   +1 more source

Increased risk of autism in extremely preterm children with a history of retinopathy of prematurity

open access: yesActa Paediatrica, EarlyView.
Abstract Aim To investigate the association between retinopathy of prematurity and autism spectrum disorder in extremely preterm children. Methods Data in children born extremely preterm at <28 weeks’ gestational age in the Region Västra Götaland, 2013–2017, were analysed for association between retinopathy of prematurity and neurodevelopmental ...
Pia Lundgren   +7 more
wiley   +1 more source

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