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[Cerebral small vessel disease].

Revue medicale suisse, 2023
Cerebral microangiopathy is the second leading cause of dementia after Alzheimer's disease and is a co-factor in the majority of dementias. Its clinical manifestations are multiple and include in addition to cognitive and neuropsychiatric manifestations, also problems of gait, urinary continence, and lacunar-ischaemic and haemorrhagic strokes. Patients
Leonardo, Caranzano, Patrik, Michel
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Genetics of common cerebral small vessel disease

Nature Reviews Neurology, 2022
Cerebral small vessel disease (cSVD) is a leading cause of ischaemic and haemorrhagic stroke and a major contributor to dementia. Covert cSVD, which is detectable with brain MRI but does not manifest as clinical stroke, is highly prevalent in the general population, particularly with increasing age.
Constance Bordes   +3 more
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Hereditary cerebral small vessel diseases: A review

Journal of the Neurological Sciences, 2012
Cerebral microangiopathies are responsible of a great number of strokes. In the recent years advances in molecular genetics identified several monogenic conditions involving cerebral small vessels and predisposing to ischemic and/or hemorrhagic stroke and diffuse white matter disease leading to vascular dementia.
FEDERICO, ANTONIO   +5 more
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Nonhypertensive Cerebral Small-Vessel Disease

Stroke, 1997
Background and Purpose Cerebral small-vessel disease (SVD) is a common aging phenomenon that is exacerbated by hypertension and diabetes mellitus. It is regarded as an important cause of lacunar infarction and intracerebral hemorrhage.
G A, Lammie   +3 more
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Prevention of Cerebral Small Vessel Disease

Seminars in Neurology, 2017
AbstractCerebral small vessel disease can cause either ischemic stroke or intracerebral hemorrhage. Accounting for up to 25% of all strokes, it is also the second biggest contributor to the risk of dementia, and is the most common incidentally discovered finding on brain imaging.
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Cerebral Small-Vessel Disease in Neuro-Behçet Disease

Journal of Stroke and Cerebrovascular Diseases, 2015
Involvement of central nervous system is very common in Behçet disease, known as neuro-Behçet disease (NBD). However, there have been few reports which evaluated stroke-like cerebral small-vessel disease associated with Behçet disease.We evaluated cerebral small-vessel lesions by using magnetic resonance imaging in 2 patients with NBD.In a 41-year-old ...
Sohei Yoshimura   +4 more
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Hereditary cerebral small vessel disease and stroke

Clinical Neurology and Neurosurgery, 2017
Cerebral small vessel disease is considered hereditary in about 5% of patients and is characterized by lacunar infarcts and white matter hyperintensities on MRI. Several monogenic hereditary diseases causing cerebral small vessel disease and stroke have been identified. The purpose of this systematic review is to provide a guide for determining when to
Søndergaard, Christian Baastrup   +3 more
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Cerebral Small Vessel Disease

2014
Small vessel disease is an important frontier in neurology; about 25% of strokes are classified as small vessel, and SVD is the most common cause of vascular cognitive impairment. The risk of developing SVD increases with age, making this a growing concern for countries with aging populations. Despite this, there has been a paucity of information about
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Cerebrovascular disease: Neuroimaging of cerebral small vessel disease

2019
The cerebral microvasculature is exceptionally vulnerable to changes due to aging. Both the radiological and clinical manifestations of cerebral small vessel disease (cSVD) in older age are highly heterogeneous, ranging from no symptomatology to devastating neurocognitive complications, including stroke, dementia, and depression.
C Elizabeth, Shaaban   +4 more
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Antiplatelet Therapy in Cerebral Small Vessel Disease

Current Neurology and Neuroscience Reports, 2019
We critically evaluate the evidence for the use of antiplatelet therapy for stroke prevention following lacunar stroke and in patients with hemorrhage-prone cerebral small vessel disease.Pooled lacunar stroke subgroup analyses of all relevant randomized controlled trials to date suggest a 22% relative risk reduction in recurrent stroke by single ...
Danielle de Sa, Bouasquevisque   +2 more
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