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Neurosurgery Clinics of North America, 2014
Cerebral vasospasm causes delayed ischemic neurologic deficits after aneurysmal subarachnoid hemorrhage. This is a well-established clinical entity with significant associated morbidity and mortality. The underlying patholphysiology is highly complex and poorly understood.
Christopher D, Baggott +1 more
exaly +3 more sources
Cerebral vasospasm causes delayed ischemic neurologic deficits after aneurysmal subarachnoid hemorrhage. This is a well-established clinical entity with significant associated morbidity and mortality. The underlying patholphysiology is highly complex and poorly understood.
Christopher D, Baggott +1 more
exaly +3 more sources
The pathophysiology of cerebral vasospasm
British Journal of Neurosurgery, 1995The current state of knowledge about the physiology, pathology and treatment of cerebral vasospasm is reviewed.
exaly +3 more sources
Journal of Neuroscience Nursing, 1980
Because previous studies suggest that prostaglandins (PGs) are involved in the contraction of cerebral arteries, the present study was undertaken to assess the direct effects of arachidonic acid, the precursor of PGs, on isolated dog basilar arteries and to ascertain the actions of three prostaglandin synthesis inhibitors, aspirin, indomethacin, and ...
M K, Gerk, N F, Kassell
+6 more sources
Because previous studies suggest that prostaglandins (PGs) are involved in the contraction of cerebral arteries, the present study was undertaken to assess the direct effects of arachidonic acid, the precursor of PGs, on isolated dog basilar arteries and to ascertain the actions of three prostaglandin synthesis inhibitors, aspirin, indomethacin, and ...
M K, Gerk, N F, Kassell
+6 more sources
Current Opinion in Anaesthesiology, 2016
With recent research trying to explore the pathophysiologic mechanisms behind vasospasm, newer pharmacological and nonpharmacological treatments are being targeted at various pathways involved. This review is aimed at understanding the mechanisms and current and future therapies available to treat vasospasm.Computed tomography perfusion is a useful ...
Ganne S Umamaheswara, Rao +1 more
openaire +2 more sources
With recent research trying to explore the pathophysiologic mechanisms behind vasospasm, newer pharmacological and nonpharmacological treatments are being targeted at various pathways involved. This review is aimed at understanding the mechanisms and current and future therapies available to treat vasospasm.Computed tomography perfusion is a useful ...
Ganne S Umamaheswara, Rao +1 more
openaire +2 more sources
Pathogenesis of Cerebral Vasospasm
Neurological Research, 1980Cerebral arteries have been shown to react to experimental subarachnoid hemorrhage with a nonspecific arterial injury reaction characterized by endothelial cell desquamation, adherence of platelets to the exposed collagen, subendothelial edema, and medial necrosis.
J F, Alksne, P J, Branson
openaire +2 more sources
Neurosurgery Clinics of North America, 1998
Established vasospasm is refractory to vasodilators, although certain agents (nimodipine or papavarine) may reverse early vasospasm when administered in high local concentrations. Calcium channel antagonists do not affect the incidence of arteriographic vasospasm and probably improve outcome by other mechanisms.
openaire +2 more sources
Established vasospasm is refractory to vasodilators, although certain agents (nimodipine or papavarine) may reverse early vasospasm when administered in high local concentrations. Calcium channel antagonists do not affect the incidence of arteriographic vasospasm and probably improve outcome by other mechanisms.
openaire +2 more sources