Results 71 to 80 of about 760,534 (303)

Cerebrovascular Involvement in Systemic Sclerosis

open access: yesACR Open Rheumatology, Volume 7, Issue 4, April 2025.
Systemic sclerosis (SSc) is a chronic autoimmune rheumatic disease characterized by vascular damage, immune system dysregulation and fibrosis. The hallmark features include microvascular alterations and progressive tissue fibrosis, affecting skin, internal organs as well central and peripheral nervous system, adding to the disease's complexity and ...
Maurizio Cutolo   +4 more
wiley   +1 more source

Continuous Selective Intra-Arterial Application of Nimodipine in Refractory Cerebral Vasospasm due to Aneurysmal Subarachnoid Hemorrhage

open access: yesBioMed Research International, 2014
Background. Cerebral vasospasm is one of the leading courses for disability in aneurysmal subarachnoid hemorrhage. Effective treatment of vasospasm is therefore one of the main priorities for these patients.
S. Ott   +7 more
semanticscholar   +1 more source

Subarachnoid hemorrhage. Modern view on intensive therapy

open access: yesВестник анестезиологии и реаниматологии, 2020
The objective: to analyze the latest data on the management of patients with subarachnoid hemorrhage (SAH).Results: nimodipine is the only drug that possesses evidence-based efficacy to prevent and treat vasospasm.
A. A. Gazenkampf   +3 more
doaj   +1 more source

Adversarial cycle-consistent synthesis of cerebral microbleeds for data augmentation [PDF]

open access: yesarXiv, 2021
We propose a novel framework for controllable pathological image synthesis for data augmentation. Inspired by CycleGAN, we perform cycle-consistent image-to-image translation between two domains: healthy and pathological. Guided by a semantic mask, an adversarially trained generator synthesizes pathology on a healthy image in the specified location. We
arxiv  

Adrenal High‐Expressional CYP27A1 Mediates Bile Acid Increase and Functional Impairment in Adult Male Offspring by Prenatal Dexamethasone Exposure

open access: yesAdvanced Science, Volume 12, Issue 14, April 10, 2025.
Prenatal dexamethasone exposure (PDE) can induce dysfunction in adrenal steroid synthesis in adult male offspring. This study demonstrate that the mechanism is associated with the upregulation of fetal adrenal cholesterol 27 hydroxylase (CYP27A1)promoter region histone 3 lysine 27 acetylation (H3K27ac) levels and expression mediated by PDE through the ...
Jiangang Cao   +7 more
wiley   +1 more source

Risk Factors Associated with Cerebral Vasospasm following Aneurysmal Subarachnoid Hemorrhage

open access: yesNeurologia medico-chirurgica, 2014
We studied the risk factors associated with cerebral vasospasm following aneurysmal subarachnoid hemorrhage (SAH). The subjects were 370 patients with ruptured aneurysms who fulfilled all of the following criteria: admission by day 2 after onset ...
T. Inagawa, K. Yahara, N. Ohbayashi
semanticscholar   +1 more source

Haemodynamic and anaesthetic management of patients undergoing endovascular therapy for cerebral vasospasm

open access: yesJournal of Neuroanaesthesiology and Critical Care, 2014
Background: Cerebral vasospasm is a common and devastating complication after a subarachnoid haemorrhage (SAH). Current guidelines for treatment recommend hypertension with euvolaemia.
Audrey Tan   +4 more
doaj   +1 more source

Segmentation of TCD Cerebral Blood Flow Velocity Recordings [PDF]

open access: yesarXiv, 2018
A binary beat-by-beat classification algorithm for cerebral blood flow velocity (CBFV) recordings based on amplitude, spectral and morphological features is presented. The classification difference between 15 manually and algorithmically annotated CBFV records is around 5%.
arxiv  

Accelerated biological aging, healthy behaviors, and genetic susceptibility with incidence of stroke and its subtypes: A prospective cohort study

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
This study identifies a significant association between accelerated biological aging, measured by clinical biomarker‐based KDM‐BA and PhenoAge accelerations, and an increased risk of stroke and its subtypes. The combination of accelerated biological aging with high genetic risk helps identify high‐risk populations on stroke development.
Xuening Zhang   +8 more
wiley   +1 more source

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