Results 271 to 280 of about 85,152 (354)

Anti‐PF4 disorders: Pathogenesis, diagnosis and treatment

British Journal of Haematology, EarlyView.
Anti‐platelet factor 4 (PF4) disorders include heparin‐induced thrombocytopenia (HIT) and vaccine‐induced immune thrombocytopenia and thrombosis (VITT)/VITT‐like disorders. The formation of immunoglobulin G (IgG)/PF4 immune complexes facilitates uncontrolled activation of platelets, neutrophils and monocytes via IgG‐mediated Fcγ receptor binding.
Megan V. Preece, Devi V. Pathak, Mike Laffan, Deepa J. Arachchillage   +3 more
wiley   +1 more source

The value of black-blood MRI in cerebral venous thrombosis diagnosis: A systematic review and meta-analysis.

Neuroradiol J
Akhavi Milani A, Mehrtabar S, Jalili J.
europepmc   +1 more source

Carotid occlusion for the management of a spontaneous carotid-cavernous fistula occurring in a single functional internal carotid artery. [PDF]

Radiol Case Rep
Srhiri S, Boubekri N, Chahdi HO, Chaouche I, Akammar A, Bouardi NE, Alami B, Boubbou M, Maaroufi M, Alaoui MYL.   +9 more
europepmc   +1 more source

Nodal peripheral T‐cell lymphoma in Finland between 2007 and 2019: Incidence, late morbidity and survival

British Journal of Haematology, EarlyView.
Summary Data on late morbidity and survival in nodal peripheral T‐cell lymphoma (PTCL) are scarce. This study investigated the incidence, subtype distribution, late morbidity and survival outcomes of nodal PTCL in Finland. The study compared 998 patients with nodal PTCL diagnosed between 2007 and 2019 with matched controls.
Anu Partanen, Aino Rönkä, Anna Anttalainen, Liisa Ukkola‐Vuoti, Iiro Toppila, Hanne Kuitunen, Tatu Miettinen, Outi Kuittinen   +7 more
wiley   +1 more source

Sequential and coexisting bilateral suboccipital cavernous sinus arteriovenous fistulas successfully treated with unilateral transvenous coil embolization: illustrative case. [PDF]

J Neurosurg Case Lessons
Ogura R, Okamoto K, Takino T, Suzuki T, Hasegawa H, Oishi M.   +5 more
europepmc   +1 more source

Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke

Brain Pathology, EarlyView.
After ischemic stroke, TRPV4 activation induces cerebral edema through the TRPV4‐RhoA‐MMP9 axis: RhoA upregulates MMP9, which cleaves β‐DG to impair membrane anchoring. Subsequent β‐DG loss triggers AQP4 depolarization, disrupting GS‐mediated water homeostasis.
Yongchuan Li, Haiping Zhou, Jiaxin Xie, Mingjia Yu, Guanyu Ye, Yuzhen Zhang, Zhentong Li, Kunxue Zhang, Jingwen Wu, Sheng Xiao, Shuxin Zeng, Yuan Chang, Kaibin Huang, Suyue Pan   +13 more
wiley   +1 more source

Vasodilator-induced selective pulmonary oedema in sarcoidosis-associated pulmonary hypertension with pulmonary venous stenosis. [PDF]

Thorax
Kiko T, Tsuji A, Ueda J, Ohta-Ogo K, Ogo T.   +4 more
europepmc   +1 more source

Site‐specific m6A‐miR‐494‐3p, not unmethylated miR‐494‐3p, compromises blood brain barrier by targeting tight junction protein 1 in intracranial atherosclerosis

British Journal of Pharmacology, EarlyView.
Background and Purpose Intracranial atherosclerosis is one of the most common causes of ischaemic stroke. However, there is a substantial knowledge gap on the development of intracranial atherosclerosis. Intracranial arteries are characterized by an upregulation of tight junctions between endothelial cells, which control endothelial permeability.
Tamar Woudenberg, M. Leontien van der Bent, Veerle Kremer, Ingeborg S. E. Waas, Mat J. A. P. Daemen, Reinier A. Boon, Paul H. A. Quax, A. Yaël Nossent   +7 more
wiley   +1 more source

Anomalous Origin of the Artery of Davidoff and Schechter Confirmed in a Case of Dural Arteriovenous Fistula of the Superior Sagittal Sinus. [PDF]

Cureus
Indo M, Oya S, Kakuda N, Tanaka M, Nemoto S.   +4 more
europepmc   +1 more source

Phosphodiesterase 3 inhibitors boost bone outgrowth

British Journal of Pharmacology, EarlyView.
Background and Purpose C‐type natriuretic peptide (CNP) stimulates skeletal growth by acting on the growth plates of long bones, and a CNP variant is clinically used for achondroplasia treatment. We previously reported that CNP stimulates the autonomic Ca2+ influx mediated by TRPM7 channels in growth plate chondrocytes to facilitate extracellular ...
Takaaki Kawabe, Atsuhiko Ichimura, Tomoki Yasue, Jianhong Li, Haruki Ishikawa, Ga Eun Kim, Hiroki Nagatomo, Naoto Minamino, Yohei Ueda, Hiromu Ito, Miyuki Nishi, Hiroshi Takeshima   +11 more
wiley   +1 more source