Results 121 to 130 of about 676,555 (236)

Expert Consensus on the Diagnosis and Monitoring of Paroxysmal Nocturnal Hemoglobinuria (PNH): An Algorithmic Approach in an Era of New Treatments

European Journal of Haematology, EarlyView.
ABSTRACT Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disorder caused by a defect of glycosylphosphatidyl‐anchored proteins, leading to an uncontrolled complement‐mediated hemolysis. The advent of complement inhibitors in clinical practice radically changed patients' outcomes and survival.
Bruno Fattizzo, Monia Marchetti, Elisa Cannizzo, Arianna Gatti, Massimo Geuna, Anna Paola Iori, Maddalena Raia, Simona Sica, Francesco Buccisano   +8 more
wiley   +1 more source

Neonatal Cerebral Venous Thrombosis

, 1992
The clinical presentation and management of 7 neonates with idiopathic cerebral venous thrombosis (CVT) are reported from the Floating Hospital for Infants and Children, New England Medical Center Hospitals, Tufts University School of Medicine, Boston ...
J Gordon Millichap
core   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

Obstetric cerebral venous thrombosis [PDF]

, 2006
Pregnancy and puerperium are most prevalent prothrombotic states leading to cerebral venous thrombosis. Likelihood of stroke to be of venous origin is greater in stroke associated with pregnancy compared to stroke unrelated to pregnancy.
Khealani, Bhojo, Sultanali, Rozina Sikandar, Mapari, Uzma U   +2 more
core  

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland, Samuel J. Belfer, Christine K. Fox, Samantha L. Irwin, Rachel Vassar, Ann Oh, Sruthi Ilangovan, Amy A. Gelfand   +7 more
wiley   +1 more source

Safety and Efficacy of Right‐ Versus Left‐Sided Transvenous Lead Extraction

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background and Aims Transvenous lead extraction (TLE) is increasingly performed for malfunction or infection of cardiac implantable electronic devices. Because of anatomic differences, TLE for right‐sided (RS) electrodes may differ in outcome. This study aimed to evaluate whether RS TLE differs in patient characteristics and outcomes compared ...
Nadine Molitor, Caroline Wiederkehr, Jan Steffel, Andreas Häberlin, Alexander Breitenstein, Daniel Hofer   +5 more
wiley   +1 more source

Rituximab induced cerebral venous sinus thrombosis in a patient with anti-N-methyl-d-aspartate receptor-antibody encephalitis: a case report and review of literature

Journal of Medical Case Reports
Background Cerebral venous sinus thrombosis has not been reported in anti-N-methyl-d-aspartate receptor-antibody encephalitis in the absence of an underlying thrombotic state while rituximab induced cerebral venous sinus thrombosis is rarely reported. We
S. Maathury, R. Thevarajah, T. Chang
doaj   +1 more source

Superior sagittal sinus filling defect in metastatic lung cancer: tumour thrombus, bland thrombus or both?

European Journal of Case Reports in Internal Medicine
Background: Cerebral venous sinus thrombosis is an uncommon but potentially life-threatening cause of stroke. In patients with active malignancy, dural venous sinus filling defects present a diagnostic challenge, as they may represent bland thrombosis ...
Haseeb Tareen, Mohammad Qarmout, Sharvana Aryal, Jody Zak, Haris Bin Tahir, Hafsa Ahmed, Adam Forman   +6 more
doaj   +1 more source

Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025)

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT With the accelerating population aging, the number of older adult patients with lung cancer continues to increase. These patients often present with multiple chronic diseases and geriatric syndromes, resulting in more complex perioperative management and significantly increased surgical risks.
Daiping Li, Rui Liang, Birong Dong, Lunxu Liu, Ning Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +6 more
wiley   +1 more source

Diagnosis and Management of Cerebral Venous Thrombosis

, 2011
Background— The purpose of this statement is to provide an overview of cerebral venous sinus thrombosis and to provide recommendations for its diagnosis, management, and treatment.
Robert D. Brown, Fernando Barinagarrementeria, Jose M. Ferro, Gustavo Saposnik, Gabrielle deVeber, Cheryl D. Bushnell, Brett Cucchiara, Mary Cushman, Fong Y. Tsai   +8 more
core   +1 more source