Results 91 to 100 of about 161,478 (359)

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Functional role for Taz during hindbrain ventricle morphogenesis.

PLoS ONE
The brain ventricle system, composed of the ventricular cavities and the cerebral spinal fluid within, performs critical functions including circulation of nutrients, removal of wastes, and cushioning of neural tissues.
Renée Dicipulo, Lyndsay G Selland, Rowan G Carpenter, Andrew J Waskiewicz   +3 more
doaj   +1 more source

Choroid plexus papilloma in a Rottweiler: computed tomographic, gross morfological and histological features

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2013
Among the tumors affecting the choroid plexus in dogs, the papilloma ranks second place in incidence after cell carcinoma tumors. Presumptive diagnosis can be made through imaging methods, such as computed tomography and magnetic resonance images ...
A.C.B.C. Fonseca Pinto, L.A. Villamizar, C.O. Ghirelli, T.R.C. Silva, C.O. Baroni, G.P.R. Banon, J.M. Guerra, C.T. Amaral, L.N. Torres   +8 more
doaj   +1 more source

Brain tumors induced in rats by human adenovirus type 12 [PDF]

, 1974
Oncogenesis of human adenovirus type 12 in the brain of rats was examined. Newborn rats of Sprague-Dawley and Donryu　strains were injected intracranially with human adenovirus type 12.　The incidence of intracranial tumors was 91% (30/33) in
Matsuo, Keisuke, Murao, Tsuyoshi, Ogawa, Katsuo, Ohmori, Hiroyuki, Sonobe, Hiroshi, Tsutsumi, Akira   +5 more
core   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Hematocrit: another important factor in systemic neonatal cardiovascular adaptation

Journal of Pediatric and Neonatal Individualized Medicine, 2019
Background: Global cardiovascular adaptation of normal healthy term newborns is rarely studied from a multiorgan and hematological point of view. Aims: To evaluate comprehensive neonatal cardiovascular adaptation during the first days of life with ...
Domenico Antonio Agostino, Raphaël Thomasset, Keiji Suzuki, Vanessa Feudo, Giuseppe Guaglianone, Fabrizio Drago, Cesare Greco, Paolo Versacci, Flavia Ventriglia, Marilisa Biolcati, Ambrogio Di Paolo   +10 more
doaj   +1 more source

Diffusion imaging and tractography of congenital brain malformations. [PDF]

, 2010
Diffusion imaging is an MRI modality that measures the microscopic molecular motion of water in order to investigate white matter microstructure.
Barkovich, A James, Mukherjee, Pratik, Wahl, Michael   +2 more
core   +3 more sources

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Concurrent Coronary, Left Ventricle, and Cerebral Thrombosis – A Trilogy

, 2022
Monika Bhandari, Akshyaya Pradhan, Pravesh Vishwakarma, Rishi Sethi   +3 more
openalex   +2 more sources

Neuroprotective Properties of Xenon. [PDF]

, 2020
Xenon is a rare noble gas that was introduced into clinical practice more than 70 years ago. Xenon's clinical properties are predicated by its ability to fit into preformed cavities of macromolecules thereby altering their biological functions.
Laitio, Timo, Maze, Mervyn
core