Results 261 to 270 of about 91,068 (335)

Continuous Infusion of β-Amyloid Protein into the Rat Cerebral Ventricle Induces Learning Impairment and Neuronal and Morphological Degeneration

, 1997
Atsumi Nitta, Taneo Fukuta, Takaaki Hasegawa, Toshitaka Nabeshima   +3 more
openalex   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Apolipoprotein e deficiency leads to altered brain uptake of alpha tocopherol injected into lateral cerebral ventricles

, 2007
Govind T. Vatassery, Hung T. Quach, William E. Smith, Karen S. SantaCruz, Sabita Roy   +4 more
openalex   +2 more sources

Velocity Spectrum Imaging Using Velocity Encoding Preparation Pulses

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose The goal of this article is to introduce a technique to measure the velocity distribution of water inside each voxel of an MR image. The method is based on the use of motion sensitizing gradients with changing first moment to encode velocity. As such, it is completely non‐invasive and requires no contrast injections.
Luis Hernandez‐Garcia, Alberto L. Vazquez, Douglas C. Noll   +2 more
wiley   +1 more source

Neuropsychiatric Systemic Lupus Erythematosus With Early-Onset Brain Atrophy: A Case Report and Literature Review. [PDF]

Cureus
AlDairi KS, Bakhsh RA, Naguib JS, Alharthi SS, Almutairi MG, Alzubaidi LR, Elamin Hassabelrasoul RK, Alhindi OS, Alharazi RA.   +8 more
europepmc   +1 more source

Bilateral Transcranial Doppler Monitoring During Neonatal Cardiac Surgery; Guidance for Clinical and Scientific Use

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Neonates undergoing cardiac surgery face a high risk of neurological injury and neurodevelopmental complications. Transcranial Doppler monitoring is used and validated in adults to measure cerebral blood flow and can provide valuable insights into cerebral perfusion in neonates.
B. V. Martherus, T. Alderliesten, E. M. R. Fonteyn, I. Ceelie, D. J. van Vriesland, J. Nijman, H. Talacua, R. A. J. Nievelstein, J. Dudink, M. J. N. L. Benders, W. F. F. A. Buhre, K. van Loon   +11 more
wiley   +1 more source

Evaluation of Fever of Unknown Origin in an Infant: Can a Case Be Made for Ultrasound of the Head as a Second-Tier Test for Meningitis? [PDF]

Cureus
Osborne AF, Jordan MA, Perdigon O, Byrd AN, Rathore M.   +4 more
europepmc   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Ruptured Anterior Communicating Artery Aneurysm in an Elderly Patient With Cerebrovascular Anomalies: A Case for Palliative Management. [PDF]

Cureus
Aakef AJ, Darayseh R, Al Shamsi A, Al Shehhi H, A K, Al Ani AO, Khalil SI.   +6 more
europepmc   +1 more source