AQP1 and AQP4 Contribution to Cerebrospinal Fluid Homeostasis
Aquaporin 1 (AQP1), expressed in epithelial cells of the choroid plexus, and aquaporin 4 (AQP4) present in ependymal cells and glia limitants have been proposed to play a significant role in cerebrospinal fluid (CSF) production and homeostasis.
José Luis Trillo-Contreras +3 more
doaj +1 more source
We provide a study comparison between two-dimensional measurement and volumetric (3D) segmentation of the lateral ventricles and brain structures in fetuses with isolated and non-isolated ventriculomegaly with 3D virtual organ computer-aided analysis ...
George Hadjidekov +5 more
doaj +1 more source
Bi-allelic GAD1 variants cause a neonatal onset syndromic developmental and epileptic encephalopathy. [PDF]
Developmental and epileptic encephalopathies are a heterogeneous group of early-onset epilepsy syndromes dramatically impairing neurodevelopment. Modern genomic technologies have revealed a number of monogenic origins and opened the door to therapeutic ...
Alix, E +30 more
core +2 more sources
Murine MPDZ-linked hydrocephalus is caused by hyperpermeability of the choroid plexus. [PDF]
Though congenital hydrocephalus is heritable, it has been linked only to eight genes, one of which is MPDZ Humans and mice that carry a truncated version of MPDZ incur severe hydrocephalus resulting in acute morbidity and lethality.
Byrne, Matthew D. +17 more
core +2 more sources
Usefulness of intravoxel incoherent motion MRI for visualizing slow cerebrospinal fluid motion
Background In the cerebrospinal fluid (CSF) dynamics, the pulsations of cerebral arteries and brain is considered the main driving force for the reciprocating bidirectional CSF movements.
Shigeki Yamada +7 more
doaj +1 more source
Aquaporin-4 and brain edema. [PDF]
Aquaporin-4 (AQP4) is a water-channel protein expressed strongly in the brain, predominantly in astrocyte foot processes at the borders between the brain parenchyma and major fluid compartments, including cerebrospinal fluid (CSF) and blood.
A Lehmenkuhler +38 more
core +2 more sources
QUANTITATIVE DEVELOPMENT of CHOROID PLEXUSES IN CHICK EMBRYO CEREBRAL VENTRICLES
Quantitative development of choroid plexuses in cerebral ventricles of chick embryos was investigated by means of the planary projection of the choroid plexuses from the time the plexuses reached a consistent flattened structure.
F. Št̆astný, Zděnek Rychter
semanticscholar +1 more source
In vivo metabolic imaging of Traumatic Brain Injury. [PDF]
Complex alterations in cerebral energetic metabolism arise after traumatic brain injury (TBI). To date, methods allowing for metabolic evaluation are highly invasive, limiting our understanding of metabolic impairments associated with TBI pathogenesis ...
Chaumeil, Myriam M +7 more
core +2 more sources
Evaluation of local and global atrophy measurement techniques with simulated Alzheimer's disease data [PDF]
The main goal of this work was to evaluate several well-known methods which provide global (BSI and SIENA) or local (Jacobian integration) estimates of atrophy in brain structures using Magnetic Resonance images.
Camara, O. +6 more
core
Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography [PDF]
Accurate identification of ischemic penumbra will improve stroke patient selection for reperfusion therapies and clinical trials. Current magnetic resonance imaging (MRI) techniques have limitations and lack validation.
Barrie Condon +9 more
core +1 more source

