Results 141 to 150 of about 329,705 (242)

Cerebrospinal fluid markers link to synaptic plasticity responses and Alzheimer's disease genetic pathways. [PDF]

open access: yesMol Neurodegener
Kirsebom BE   +22 more
europepmc   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

open access: yesAdvanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera   +12 more
wiley   +1 more source

Cerebrospinal fluid analysis in tuberculous meningitis: A literature review. [PDF]

open access: yesSurg Neurol Int
Imron A   +4 more
europepmc   +1 more source

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

open access: yesAdvanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng   +4 more
wiley   +1 more source

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie   +18 more
wiley   +1 more source

THE CEREBROSPINAL FLUID IN SYPHILIS [PDF]

open access: yesJournal of Experimental Medicine, 1913
Arthur W. M. Ellis, Homer F. Swift
openaire   +3 more sources

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