Results 151 to 160 of about 395,728 (365)

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

Advanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu, Danming He, Zan Hou, Mei Lan, Ye Zhang, Qifeng Wang   +5 more
wiley   +1 more source

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

Advanced Science, EarlyView.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He, Bin Wu, Liuhu Han, Mingde Li, Wenli Guo, Jiajing Fu, Bin Mei, Eric R. Gross, Xuesheng Liu, Yao Lu   +9 more
wiley   +1 more source

Selected acute phase CSF factors in ischemic stroke: findings and prognostic value

BMC Neurology, 2011
Background Study aimed at investigation of pathogenic role and prognostic value of several selected cerebrospinal fluid acute phase factors that can reflect the severity of ischemic brain damage.
Intskirveli Nino, Shakarishvili1 Roman, Sanikidze Tamar, Beridze Maia, Bornstein Natan M   +4 more
doaj   +1 more source

Evidence for the Release of Vasopressin and Oxytocin into Cerebrospinal Fluid: Measurements in Plasma and CSF of Intact and Hypophysectomized Rats [PDF]

, 1977
J. Dogterom, Tj. B. van Wimersma Greidanus, Dick F. Swaab   +2 more
openalex   +1 more source

A Novel Cranial Bone Transport Technique Repairs Skull Defect and Minimizes Brain Injury Outcome in Traumatic Brain Injury Rats

Advanced Science, EarlyView.
This study introduces a novel, safe, and effective surgical technique: Cranial bone transport (CBT) to improve traumatic brain injury (TBI) outcomes in rats. CBT significantly accelerated skull defect bone repair in addition to its promoting effects on neurological function recovery. This work provides an alternative therapy for patients suffering from
Shanshan Bai, Xuan Lu, Xu Yan, Han Su, Yuejun Lin, Zhaowei Jiang, Zhixian Zong, Haixing Wang, Leo Yik Chun Yan, Xiaoting Zhang, Ming Wang, Zhengmeng Yang, Jiakang Jin, Yaofeng Wang, Wayne Yuk‐Wai Lee, Xiaohua Jiang, Ho Ko, Lu Feng, Micky D. Tortorella, Sien Lin, Gang Li   +20 more
wiley   +1 more source

FGF2 is expressed in human and murine embryonic choroid plexus and affects choroid plexus cell behaviour [PDF]

, 2008
Background Although fibroblast growth factor (Fgf) signalling plays crucial roles in several developing and mature tissues, little information is currently available on expression of Fgf2 during early choroid plexus development and whether Fgf2 directly ...
Ferretti, P., Greenwood, S., Swetloff, A., Terasaki, T., Wade, A.   +4 more
core   +3 more sources

Nasal Delivery of Engineered Exosomes via a Thermo‐Sensitive Hydrogel Depot Reprograms Glial Cells for Spinal Cord Repair

Advanced Science, EarlyView.
Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang, Jingsong Liu, Pengfei Li, Zhibin Peng, Yubo Zhang, Yishu Liu, Mi Li, Xuqiang Gong, Daqian Liu, Enze Xu, Hongbo Yang, Yuanliang Sun, Yan Xu, Yansong Wang   +13 more
wiley   +1 more source

Review of "Proteins of the Cerebrospinal Fluid" (2^nd Edition) by Edward J. Thompson

Cerebrospinal Fluid Research, 2007
This book on cerebrospinal fluid (CSF) proteins is primarily focused on immunoglobulins. The book was written as an extension of a meeting on multiple sclerosis to provide a more extensive consideration of the CSF.
Connor James R
doaj   +1 more source

Highly accurate blood test for Alzheimer’s disease is similar or superior to clinical cerebrospinal fluid tests

Nature Network Boston
With the emergence of Alzheimer’s disease (AD) disease-modifying therapies, identifying patients who could benefit from these treatments becomes critical.
Nicolas R. Barthélemy, Gemma Salvadó, S. Schindler, Yingxin He, S. Janelidze, L. Collij, B. Saef, Rachel L. Henson, Charles D. Chen, B. Gordon, Yan Li, R. La Joie, T. Benzinger, John C. Morris, N. Mattsson-Carlgren, S. Palmqvist, R. Ossenkoppele, G. Rabinovici, E. Stomrud, Randall J. Bateman, O. Hansson   +20 more
semanticscholar   +1 more source

Further studies of the fluorescent treponemal antibody-cerebrospinal fluid (FTA-CSF) test with a monospecific anti-IgM conjugate. [PDF]

, 1973
W. P. Duncan, U. S. G. Kuhn
openalex   +1 more source