Neuroleukemiosis Masquerading as Drug Toxicity in an Adolescent With Refractory AML
American Journal of Hematology, EarlyView.
Nia Choi +11 more
wiley +1 more source
Annals of Neurology, EarlyView.Synthesis of Literature: Neurodegeneration in Moderate‐Severe TBI. Objective Although moderate‐to‐severe traumatic brain injury (msTBI) was once considered a static neural event following resolution of acute injuries, numerous studies now demonstrate progressive losses to volume and white matter integrity in the months and years postinjury, leading to ...
Bhanu Sharma +4 more
wiley +1 more source
Clinical utility of CSF Aβ38 in Japanese research and clinical cohorts
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease MonitoringINTRODUCTION Previous studies have reported that cerebrospinal fluid (CSF) amyloid beta (Aβ42/Aβ38) performs comparably to Aβ42/Aβ40 in predicting amyloid positron emission tomography (PET) positivity in White cohorts.
Tamao Tsukie +8 more
doaj +1 more source
Fluorescent treponemal antibody-cerebrospinal fluid (FTA-CSF) test. A provisional technique.
, 1972 W. P. Duncan, Tammy Jenkins, C E Parham
openalex +1 more source
Global cerebrospinal fluid circulation mapping using gold nanoparticle enhanced X-ray microtomography reveals region-specific brain and spinal cord CSF pathways [PDF]
, 2021 Shelei Pan +17 more
openalex +1 more source
Timing of Changes in Alzheimer's Disease Plasma Biomarkers as Assessed by Amyloid and Tau PET Clocks
Annals of Neurology, EarlyView.Objective The objective of this study was to evaluate the timing of change of Alzheimer's disease (AD) plasma biomarkers (Aβ42/Aβ40, p‐tau217, p‐tau181, GFAP, and NfL) from six different assay platforms, alongside established AD biomarkers, using amyloid and tau positron emission tomography (PET)‐based AD progression timelines.
Marta Milà‐Alomà +27 more
wiley +1 more source
Blood α‐Synuclein Separates Parkinson's Disease from Dementia with Lewy Bodies
Annals of Neurology, EarlyView.Objective Aggregation of misfolded α‐synuclein (aSyn) within the brain is the pathologic hallmark of Lewy body diseases (LBDs), including Parkinson's disease (PD), and dementia with Lewy bodies (DLB) disease. Although evidence exists for aSyn “strains,” conformations with distinct biological properties, biomarkers for PD versus DLB are lacking.
George T. Kannarkat +17 more
wiley +1 more source
Single‐Molecule Protein Profiling Using Nanopores and Dimeric Aptamer‐Modified DNA Carriers
Angewandte Chemie, EarlyView.We developed a nanopore‐based biosensor for single‐molecule protein profiling using aptamer‐modified DNA carrier dimerization strategy, enabling selective and ultrasensitive detection of proteins and protein complexes. This approach promises advances in early‐stage clinical diagnostics and precision medicine.
Xiaoyi Wang +4 more
wiley +2 more sources
Accurate Detection of Cerebrospinal Fluid by DNA Aptamers Derived by Clinical Samples
International Forum of Allergy &Rhinology, EarlyView.
Xinlei Chen +9 more
wiley +1 more source
Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy
Annals of Neurology, EarlyView.Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal +7 more
wiley +1 more source