A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo +18 more
wiley +1 more source
Catheter-assisted sealing technique for spontaneous cerebrospinal fluid leaks: A novel neurointerventional treatment of spontaneous cerebrospinal fluid leak beyond cerebrospinal fluid-venous fistula. [PDF]
Zanaty M +9 more
europepmc +1 more source
A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati +10 more
wiley +1 more source
Hyperostosis Cranialis Interna Presenting With Cerebrospinal Fluid Leak: A Case Report and Review of Literature. [PDF]
Alsaleh AS, BinGhaith AI, Alsuliman Y.
europepmc +1 more source
POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley +1 more source
Efficacy of a synthetic collagen-based sealant (TachoSil<sup>®</sup>) in preventing cerebrospinal fluid leak following planned and incidental durotomies in spine surgery: a retrospective cohort study. [PDF]
Delgado-López PD +6 more
europepmc +1 more source
Proteomic dysregulation associated with cerebral amyloid angiopathy
Abstract INTRODUCTION Cerebral amyloid angiopathy (CAA) is characterized by impaired vascular amyloid‐β clearance, distinct from Alzheimer's disease (AD), underscoring the need to clarify its molecular basis for predicting therapy‐related amyloid‐related imaging abnormalities. METHODS We analyzed post‐mortem brain proteomics from Religious Orders Study
Sang‐Won Han +8 more
wiley +1 more source
Minimally Invasive Transdural Closure of a Ventral Spinal Cerebrospinal Fluid Leak in Spontaneous Intracranial Hypotension: 2-Dimensional Operative Video. [PDF]
Häni L +5 more
europepmc +1 more source
Acta Paediatrica, Volume 115, Issue 11, Page 2640-2643, November 2026.
Robert Cohen +8 more
wiley +1 more source
Abstract Alzheimer's disease (AD) is accompanied by persistent disturbances in brain energy metabolism, and microglial glucose metabolic reprogramming constitutes an important link among pathological protein deposition, neuroinflammation, and impaired clearance.
Yuan Chen +8 more
wiley +1 more source

