Results 81 to 90 of about 16,667 (247)

Two Cases of Cerebrospinal Fluid Rhinorrhea Repair Surgery Using TachoComb [PDF]

Journal of Rhinology
Cerebrospinal fluid (CSF) rhinorrhea is a rare condition characterized by the leakage of CSF through the nose. The diagnosis is established through comprehensive history taking, brain imaging, and nasal endoscopy.
Ah Young Bae, Sun Hong Kim, Se Hwan Hwang   +2 more
doaj   +1 more source

Cranial Vault and Scalp Reconstruction Utilizing Anterolateral Thigh Free Tissue Transfer

The Laryngoscope, EarlyView.
The anterolateral thigh free flap with perforator harvest and minimal access recipient vessel procurement technique offers an adaptable and effective reconstructive option for a wide variety of complex scalp and cranial vault defects. There were no significant differences in outcomes or complications of the three flap types analyzed (fasciocutaneous ...
Conrad Blunck, Stephen P. Hadford, Lacey Magee, Derek Vos, Dane J. Genther, Sarah W. Liu, Michael A. Fritz, Peter J. Ciolek   +7 more
wiley   +1 more source

Vocal Fold Atrophy in Patients With Alzheimer's Disease and Related Dementias

The Laryngoscope, EarlyView.
This is the first study to quantify vocal fold atrophy in patients with Alzheimer's disease and related dementias (AD/ADRD) using endoscopic imaging. Compared with age‐matched controls, AD/ADRD patients showed significantly greater vocal fold bowing and reduced mucosal wave amplitude, while normalized glottal gap area did not differ.
Byron Kim, Carson Miller, Shruti Dhingra, Mahdi Al‐Ghezi, Emily Wilson, Neel K. Bhatt   +5 more
wiley   +1 more source

#21. Beware the Runny Nose – Could Be CSF Leak!

Graduate Medical Education Research Journal
Mentor: Sarah Howard Program: Clarkson Family Medicine Type: Case Report Background: Cerebrospinal fluid (CSF) rhinorrhea is a rare condition in which cerebrospinal fluid leaks from the nasal cavity.
Rubab Ali, Sarah Howard
doaj   +1 more source

Altered Cerebrospinal Fluid Tryptophan–Kynurenine Pathway Metabolism in Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Alterations in tryptophan–kynurenine (TRP‐KYN) metabolism, which is associated with neuroinflammation, remain unclear in multiple system atrophy (MSA). Objective The aim was to investigate cerebrospinal fluid (CSF) TRP metabolites in MSA and their associations with other biomarkers.
Ryunosuke Nagao, Kazuya Kawabata, Yasuaki Mizutani, Sayuri Shima, Akihiro Ueda, Mizuki Ito, Yasuhiro Maeda, Akihiro Mouri, Hirohisa Watanabe   +8 more
wiley   +1 more source

Gene Therapy for Amino Acid Decarboxylase Deficiency: Clinical and Imaging Outcomes in a French Cohort

Movement Disorders, EarlyView.
Abstract Background Intracerebral gene therapy is effective for amino acid decarboxylase (AADC) deficiency, but relationships between anatomical putaminal coverage, metabolic dynamics, and clinical recovery remain poorly understood. Objectives Assess safety, long‐term efficacy, and clinical–radiological correlations in a genetically diverse European ...
Clément Dunoyer, Gaëtan Poulen, Marie‐Céline François‐Heude, Eline Chauvet‐Piat, Bérénice Lecardonnel, Emmanuel Roze, Marie‐Ange Nguyen Morel, Domitille Gras, Adeline Quintard, Gaelle Baroux, Pierre Meyer, Philippe Coubes, Christophe Milesi, Julien Baleine, Chrystelle Sola, Vivien Szabo, Bénédicte Delye, Jana Haberlova, Mohamed Osman Eltahir Babiker, Mohammed Al Muqbil, Stéphanie Sanchez, Souad Touati, Nicolas Leboucq, Virginie Kouyoumdjian, Sylvia Sanquer, Denis Mariano‐Goulart, Thomas Roujeau, Agathe Roubertie   +27 more
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Brain Clearance of Contrast Agent in Intravenous DCE‐MRI Is Measurable and Cannot Be Explained by Clearance Across the BBB Alone

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To determine the feasibility of measuring brain clearance of gadolinium contrast agent using standard intravenous DCE‐MRI acquisitions and evaluate the contribution of blood–brain barrier (BBB) and non‐BBB clearance routes. Methods Uptake and extended Tofts models were fit to DCE‐MRI data from people with Parkinson's disease, post ...
Martin Kozár, Ioana‐Emilia Mosneag, Sarah Al‐Bachari, Igor Chernyavsky, Geoff J. M. Parker, Hervé Boutin, Laura M. Parkes, Ingo Schiessl, Ben R. Dickie   +8 more
wiley   +1 more source

Pneumatization pattern of the temporal bone with volumetric assessment and its impact on the frequency of cerebrospinal fluid leak in patients undergoing vestibular schwannoma surgery via the retrosigmoid approach

Frontiers in Neurology
IntroductionVestibular schwannomas are benign tumors that account for 8% of all intracranial tumors. Due to their location in the cerebellopontine angle and internal auditory canal, access to these lesions requires disruption of the temporal bone.
Karol Zaczkowski, Rafał Wójcik, Krzysztof Tybor, Dariusz Jan Jaskólski, Karol Wiśniewski   +4 more
doaj   +1 more source

Using Manganese‐Enhanced DCE‐MRI to Assess Blood‐Cerebrospinal Fluid Barrier Transport

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose We developed a dynamic, heavily T2‐weighted (hT2w) FLAIR protocol to resolve acute Mn2+ transport kinetics, as a proxy for Ca2+, across the choroid plexus (ChP)—cerebrospinal fluid (CSF) interface, in vivo. By quantifying intercompartmental Mn2+ dynamics, and comparing these with Gd‐DOTA, we sought to characterize blood‐CSF‐barrier ...
Charith Perera, Zhiping Feng, Shereen Nizari, Phillip Muza, Christina Katsiva, Tammy L. Kalber, Mark F. Lythgoe, Ian F. Harrison, Daniel J. Stuckey, Jack A. Wells   +9 more
wiley   +1 more source