Results 101 to 110 of about 244,039 (307)

Multiplexed Bio‐detection on an Interferometric Optical Waveguide Assembly

Advanced Materials Interfaces, EarlyView.
Multiplexed remote bio‐detection is demonstrated through an image conduit composed of 3012 individual cores and coated with interferometric layers. The proof of concept of biodetection is performed through the kinetic monitoring of two complementary DNA strands hybridization paving the way for applications in multiplex in situ biosensing, and ...
Oleksii Bratash, Rémi Courson, Laurent Malaquin, Thierry Leichle, Arnaud Buhot, Loïc Leroy, Elodie Engel   +6 more
wiley   +1 more source

Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection [PDF]

, 2015
Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection.
Bizzarri, Bianca, Cardi, Veronica, DE CURTIS, Mario, Fabio, Natale, Gaeta, Aurelia, Giuseppina, Liuzzi, Paola, Villani   +6 more
core   +2 more sources

The integrated model of cAMP-dependent DNA expression reveals an inverse relationship between cancer and neurodegeneration [PDF]

arXiv, 2016
The model for cAMP-dependent synaptic plasticity relates the characterization of a noradrenaline-stimulated adenylyl cyclase with DNA unzipping. Specific proteins condition cAMP insertion in specific sites of the DNA structure to direct cellular and synaptic differentiation in brain tissues, also providing coding. Metabolic-dependent ATP binding of Mg2+
arxiv  

MENINGITE NEOPLÁSICA EM PACIENTE COM CÂNCER DE PULMÃO: ACHADOS LABORATORIAIS EM AMOSTRA DE LÍQUIDO CEFALORRAQUIDIANO

Revista Educação em Saúde, 2015
Objective: To present and analyze the sample laboratory findings of cerebrospinal fluid of patients with lung tumor. Case report and comments: Laboratory data analyzed were derived from the cerebrospinal fluid routine examination, culture, resistant acid-
Heitor Gomes de Souza Pereira, Ângela Alves Viegas   +1 more
doaj  

A chronic fatigue syndrome – related proteome in human cerebrospinal fluid

BMC Neurology, 2005
Background Chronic Fatigue Syndrome (CFS), Persian Gulf War Illness (PGI), and fibromyalgia are overlapping symptom complexes without objective markers or known pathophysiology. Neurological dysfunction is common.
Baraniuk James N, Casado Begona, Maibach Hilda, Clauw Daniel J, Pannell Lewis K, Hess S Sonja   +5 more
doaj   +1 more source

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

Advanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin, Houxin Fan, Zhenchao Liu, Paolo Donati, Youssef Amin, Yap Wing Fen, Junbo Liang, Pier Paolo Pompa, Sailing He   +8 more
wiley   +1 more source

Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles [PDF]

, 2016
Here, we identified release of extracellular vesicles (EVs) by the choroid plexus epithelium (CPE) as a new mechanism of blood-brain communication. Systemic inflammation induced an increase in EVs and associated pro-inflammatory miRNAs, including miR ...
An Hendrix, Beutler B, Claude Libert, Delphine Demeestere, Elien Van Wonterghem, Koen Raemdonck, Kris Gevaert, Liu L, Marjana Brkic, Riet De Rycke, Roosmarijn E Vandenbroucke, Seehusen DA, Sriram Balusu, Stephan Stremersch, Valerie Vanhooren   +14 more
core   +2 more sources

Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy

Frontiers in Neuroanatomy, 2014
When nanoparticles/proteins are infused into the brain, they are often transported to distal sites in a manner that is dependent both on the characteristics of the infusate and the region targeted. We have previously shown that AAV is disseminated within
Ernesto A Salegio, Ernesto A Salegio, Hillary eStreeter, Nikhil eDube, Piotr eHadaczek, Lluis eSamaranch, Adrian eKells, Waldy eSan Sebastián, Yuying eZhai, John eBringas, Ting eXu, John eForsayeth, Krystof S Bankiewicz   +12 more
doaj   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning. [PDF]

, 2016
BackgroundHuman immunodeficiency virus (HIV) and methamphetamine use commonly affect neurocognitive (NC) functioning. We evaluated the relationships between NC functioning and two fibroblast growth factors (FGFs) in volunteers who differed in HIV ...
Bharti, Ajay R, Cherner, Mariana, Ellis, Ronald J, Everall, Ian P, Grant, Igor, Heaton, Robert K, Letendre, Scott L, Masliah, Eliezer, Potter, Michael, Rosario, Debra, Woods, Steven Paul   +10 more
core   +2 more sources