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Cerebrospinal fluid proteins in multiple sclerosis

Neurology, 1975
Various CSF proteins were studied in 255 definite multiple sclerosis patients at various disease stages and compared with corresponding values obtained from 174 controls. The CSF changes in acute multiple sclerosis patients included a significant increase of total proteins and of gamma globulin, IgG, IgA, IgM, alpha-2 ceruloplasmin, 7S-gamma-1, and ...
G, Lamoureux   +4 more
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Cerebrospinal Fluid Protein Electrophoresis

2001
Cerebrospinal fluid (CSF), a clear colorless fluid with a viscosity similar to water, is produced at a rate of approx 500 mL p/d. The volume averages 135–150 mL in an adult and approx 40 mL in neonates with a turnover rate of 6 h. Approximately two-thirds of the CSF is secreted by the choroid plexuses, whereas the rest comes from leakage of plasma from
John R. Petersen, Amin A. Mohammad
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Protein size and cerebrospinal fluid composition

Klinische Wochenschrift, 1974
The concentration ratios of several proteins between serum and cerebrospinal fluid (CSF) can be correlated more easily to hydrodynamic volumes than to molweights. Hydrodynamic radii were calculated from literature diffusion data and determined by analytical column chromatography and gel electrophoresis.
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Protein Profiling of Cerebrospinal Fluid

2011
The cerebrospinal fluid (CSF) perfuses the brain and spinal cord. CSF contains proteins and peptides important for brain physiology and potentially also relevant for brain pathology. Hence, CSF is the perfect source to search for new biomarkers to improve diagnosis of neurological diseases as well as to monitor the performance of disease-modifying ...
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Cerebrospinal Fluid Proteins in Pathology

1985
Clinicians are currently showing increasing interest in the study of the CSF. This interest can be estimated from the great number of recent publications devoted to the subject.1 Human CSF proteins have been examined quantitatively and qualitatively. The quantitative examinations concern the determination of the total protein content, determinations of
A. Lowenthal, D. Karcher
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Cerebrospinal fluid proteins in muscular dystrophy patients

Brain and Development, 1984
We analyzed and quantified the microcomponents of protein fractions in the cerebrospinal fluid of patients with various types of muscular dystrophy. The degenerative pattern is characterized by an increase in the prealbumin fraction and a decrease in the gamma-globulin fraction as shown in the Duchenne and congenital muscular dystrophy. The increase in
T, Hirase, S, Araki
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Cerebrospinal fluid protein values of premature infants

The Journal of Pediatrics, 1965
The cerebrospinal fluid protein content in 71 premature infants was found to be higher than that reported for full-term newborn infants; the usual values were between 100 to 200 mg. per 100 c.c. during the first 2 weeks of life. The values fell gradually thereafter to reach accepted limits for full-term newborn infants by 2 months of age. The initially
C H, BAUER, M I, NEW, J M, MILLER
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[Cerebrospinal fluid proteins and epilepsy].

Psychiatrie, Neurologie, und medizinische Psychologie, 1982
The authors examined 54 epileptic patients with a view to prove the presence of an immunological cerebrospinal fluid syndrome. The result showed that a significant immunoglobulin depression could not be proved by means of a cerebrospinal fluid test.
M, Heim, J, Morgner
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Human cerebrospinal fluid protein database: Edition 1992

ELECTROPHORESIS, 1992
AbstractTwo‐dimensional electrophoresis maps of human cerebrospinal fluid proteins are presented in the form of labeled images. 931 protein spots are identified in spinal fluid from a normal volunteer. Distinct spots that represent variants of the same protein, especially posttranslational modifications, are estimated to reduce the 931 different spots ...
M, Yun, W, Wu, L, Hood, M, Harrington
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Cerebrospinal Fluid Protein Patterns in Spasmodic Torticollis

European Neurology, 1975
In order to investigate the value of CSF-protein analyses in spasmodic torticollis CSF from six patients with probable organic and two patients with probable psychogenic torticollis was examined by isoelectric focusing and electrophoresis. In all the patients with organic torticollis two pathological CSF-protein fractions were found in the alkaline ...
K G, Kjellin, H, Stibler
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