Results 51 to 60 of about 1,197,072 (225)
Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation
Annals of the Child Neurology Society, EarlyView.ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed +5 more
wiley +1 more source
β‐Hydroxybutyrate reduces neuronal excitability via GIRK channels
Epilepsia, EarlyView.β‐Hydroxybutyrate decreases neuronal excitability by activating GIRK channels through HCAR2 signaling, providing a cellular mechanism that may contribute to the antiseizure effects of the ketogenic diet. Abstract Objective The ketogenic diet is used to treat drug‐resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure ...
Soudabeh Naderi +8 more
wiley +1 more source
CSF Ascites: Review of articles and a case presentation
Journal of Research in Medical Sciences, 2005 Cerebrospinal fluid (CSF) ascites is a rare complication after ventriculopritoneal (VP) shunts. Most patients have gradual abdominal protrusion without any neurological sign or symptom of shunt malfunction.
R Pourkhalili, A Mirhosseini, H Khalili
doaj
CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis. [PDF]
, 2012 The cyclic nucleotides cyclic adenosine-3',5'-monophosphate (cAMP) and cyclic guanosine-3',5'-monophosphate (cGMP) are important second messengers and are potential biomarkers for Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and ...
Oeckl, Patrick +23 more
core +1 more source
Exploration, EarlyView.This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi +5 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Lower urinary tract symptoms (LUTS) are among the most prevalent nonmotor complaints across the parkinsonian spectrum, yet they remain underutilized as diagnostic and management signals in neurology practice. Although prior reviews have characterized disease‐specific patterns of urinary dysfunction, and recent guidelines address ...
Saar Anis +3 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, EarlyView.ABSTRACT Objective To characterize prenatal ultrasound findings in fetuses with prenatally diagnosed closed spinal dysraphism (CSD) and report their postnatal management and functional outcomes at 18 and 36 months. Methods This retrospective cohort study included all fetuses with a prenatal diagnosis of CSD assessed between January 2014 and December ...
Y. Athiel +15 more
wiley +1 more source
Epidural hematoma after ventriculoperitoneal shunt surgery: report of two cases
Arquivos de Neuro-Psiquiatria, 1998 Ventriculoperitoneal shunt operations represent the most used choice for treating hydrocephalus, although some related complications have been reported.
PEREIRA CARLOS UMBERTO +3 more
doaj
Egyptian Journal of Neurosurgery, 2018 Background Shunting of cerebrospinal fluid (CSF) has reduced the morbidity and mortality of hydrocephalus. Ventriculoperitoneal (VP) shunt is the most commonly used procedure for shunting, but it has potential complications that may need multiple ...
Ali R. Hamdan
doaj +1 more source
Acta Clinica Croatica, 2020 Syringomyelia is characterized by a fluid-filled cavity within the spinal cord. Expansion of the syrinx often results in the clinical course of progressive neurologic deficit.
Domagoj Jugović +3 more
doaj +1 more source