Results 41 to 50 of about 737,472 (291)

Treatment with vascular endothelial growth factor-A worsens cognitive recovery in a rat model of mild traumatic brain injury

Frontiers in Molecular Neuroscience, 2022
Mild traumatic brain injury (mTBI) is a common and unmet clinical issue, with limited treatments available to improve recovery. The cerebrovascular system is vital to provide oxygen and nutrition to the brain, and a growing body of research indicates ...
Mujun Sun, Tamara L. Baker, Campbell T. Wilson, Rhys D. Brady, Richelle Mychasiuk, Glenn R. Yamakawa, Anh Vo, Trevor Wilson, Stuart J. McDonald, Sandy R. Shultz, Sandy R. Shultz, Sandy R. Shultz   +11 more
doaj   +1 more source

Predicting blunt cerebrovascular injury in pediatric trauma: Validation of the Utah Score [PDF]

, 2017
Risk factors for blunt cerebrovascular injury (BCVI) may differ between children and adults, suggesting that children at low risk for BCVI after trauma receive unnecessary computed tomography angiography (CTA) and high-dose radiation.
Akbari, Hassan, Birkas, Yekaterina, Bollo, Robert J, Gannon, Stephen, Jea, Andrew, Kestle, John R, Limbrick, David D, Jr, Naftel, Robert P, Prather, Colin T, Ravindra, Vijay M, Riva-Cambrin, Jay, Shannon, Chevis, Sivakumar, Walavan, Yang, George L   +13 more
core   +2 more sources

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Detrimental effects of physical inactivity on peripheral and brain vasculature in humans: Insights into mechanisms, long-term health consequences and protective strategies

Frontiers in Physiology, 2022
The growing prevalence of physical inactivity in the population highlights the urgent need for a more comprehensive understanding of how sedentary behaviour affects health, the mechanisms involved and what strategies are effective in counteracting its ...
Alessio Daniele, Samuel J. E. Lucas, Samuel J. E. Lucas, Catarina Rendeiro, Catarina Rendeiro   +4 more
doaj   +1 more source

Vascular dementia: Current concepts and nomenclature harmonization. [PDF]

, 2012
Several types of cerebrovascular lesions are associated with cognitive decline, but the role of each type in dementia manifestation has yet to be determined.
Grinberg, Lea Tenenholz
core  

Evaluating hospital performance based on excess cause-specific incidence [PDF]

, 2015
Formal evaluation of hospital performance in specific types of care is becoming an indispensable tool for quality assurance in the health care system.
Eriksson, Marie, Goetghebeur, Els, Van Rompaye, Bart   +2 more
core   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Risk factors of ischemic stroke and subsequent outcome in hemodialysis patients [PDF]

, 2015
Background and purpose: End stage renal disease (ESRD) requiring hemodialysis (HD) carries up to a 10-fold greater risk of stroke than normal renal function. Knowledge concerning risk factors and management strategies derived from the general population
Dawson, Jesse, Findlay, Mark D., Fulton, Rachael L., Geddes, Colin C., Jardine, Alan G., Mark, Patrick B., Patel, Rajan K., Solbu, Marit D., Stevens, Kathryn K., Thomson, Peter C.   +9 more
core   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

Patient-Specific Modeling Could Predict Occurrence of Pediatric Stroke

Frontiers in Physiology, 2022
Moyamoya disease (MMD) is a progressive steno-occlusive cerebrovascular disease leading to recurrent stroke. There is a lack of reliable biomarkers to identify unilateral stroke MMD patients who are likely to progress to bilateral disease and experience ...
John D. Horn, Michael J. Johnson, Zbigniew Starosolski, Zbigniew Starosolski, Avner Meoded, Avner Meoded, Dianna M. Milewicz, Ananth Annapragada, Ananth Annapragada, Shaolie S. Hossain, Shaolie S. Hossain   +10 more
doaj   +1 more source