Results 91 to 100 of about 58,328 (279)

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

From multi‐omics to precision medicine in intracranial aneurysm: Biomarker discovery and multimodal integration

Interdisciplinary Medicine, EarlyView.
This review explores intracranial aneurysm biomarker discovery through multi‐omics. It reveals key genes, proteins, and metabolites, and shows how machine‐learning‐based multi‐modal integration may aid diagnosis and treatment. Abstract Despite extensive research, currently, no biomarkers are available for clinical use in intracranial aneurysm (IA ...
Jiaxin Zhang, Yufei Yang, Bingxu Chen, Yanmeng Zhao, Haitao Sun   +4 more
wiley   +1 more source

Differential Vasomotor Effects of Insulin in the Peripheral and Cerebrovascular Circulations of Healthy Young Adults

, 2021
Brian Shariffi, Jennifer L. Harper, James Smith, Sean T. Ready, Iman N. Lloyd, Camila Margarita Manrique Acevedo, Jaume Padilla, Jacqueline K. Limberg   +7 more
openalex   +1 more source

Machine Learning Reveals the Value of Unconventional T Lymphocytes in Sepsis and Prognosis of Elderly Patients With Severe Lower Respiratory Tract Infections

Journal of Clinical Laboratory Analysis, EarlyView.
Initially, 166 subjects aged 65 years or older with severe LRTIs met the diagnostic criteria, but 30 cases were excluded due to incomplete clinical data, and 17 cases were excluded due to the presence of malignancies, connective tissue diseases, or long‐term use of immunosuppressive agents. Ultimately, 119 patients were included in the study. The study
Tianqi Qi, Qian Gao, Yan Song, Yulin Li, Yanlan Yao, Xinyue Liu, Manyu Li, Jingxian Yang, Qi Hao   +8 more
wiley   +1 more source

Cerebrovascular reactivity differences in healthy cerebral gray and white matter. [PDF]

Magn Reson Med
Abstract Purpose To quantify the speed and magnitude of cerebrovascular reactivity (CVR) metrics in hemispheric gray and white matter. Methods A standardized isoxic hypercapnic cerebrovascular stimulus was administered using an automated arterial gas targeting system while monitoring blood oxygen–level dependent MRI.
Levine HT, Poublanc J, Sayin ES, Duffin J, Sobczyk O, Fisher JA, Mikulis DJ.   +6 more
europepmc   +2 more sources

The analysis of cerebrovascular circulation time using digital subtraction angiography(DSA) [PDF]

, 1986
Dongyi Han, Dong Kun Kim, H K Lee, K.H. Kwon, K J Kim   +4 more
openalex   +1 more source

Autonomic control of cerebral blood flow: fundamental comparisons between peripheral and cerebrovascular circulations in humans [PDF]

, 2021
Jodie L. Koep, Chloe E. Taylor, Jeff S. Coombes, Bert Bond, Philip N. Ainslie, Tom G. Bailey   +5 more
openalex   +1 more source

Drug Resistance and Epidemiological Analysis of Carbapenem‐Resistant Enterobacteriaceae in a Brain and Psychiatric Hospital of South China

Journal of Clinical Laboratory Analysis, EarlyView.
Detection time and department distribution of each isolate of CRKP and its clustering distribution indicator, the number codes the strain, for example 01=K2021001. ABSTRACT Background Carbapenem‐resistant Enterobacteriaceae (CRE) has increasingly become a global health problem, and the drug resistance and epidemiology of its infection are important for
Lei Yue, Xiumei Zhu, Yuyan Kuang, Yulong Lin, Haiying Liu   +4 more
wiley   +1 more source

Associations between cognitive impairment and cerebrovascular reserve in different lobes during the acute stroke of anterior circulations [PDF]

, 2022
Mengna Chu, Wei Dong, Chao Huang, Bin Dong, Ming Yao   +4 more
openalex   +1 more source

The Diagnostic Value of Contrast‐Enhanced Vessel Wall MRI for Diagnosing Neuropsychiatric Systemic Lupus Erythematosus

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Imaging biomarkers for neuropsychiatric systemic lupus erythematosus (NPSLE) are highly needed, and intracranial contrast‐enhanced vessel wall imaging (CE‐VWI) can potentially detect cerebral vessel wall abnormalities in lupus. Purpose To evaluate the diagnostic value of CE‐VWI in differentiating NPSLE from non‐NPSLE.
Satoru Ide, Yuya Fujita, Yu Murakami, Koichiro Futatsuya, Yuta Yoshimatsu, Jun Tsukamoto, Haruka Oku, Toshihiro Sakamoto, Yoshiya Tanaka, Takatoshi Aoki   +9 more
wiley   +1 more source