Results 61 to 70 of about 163,464 (311)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Calculus Bovis-Fel Uris-Moschus Pharmacopuncture’s Effect on Regional Cerebral Blood Flow and Mean Arterial Blood Pressure in Rats

Journal of Pharmacopuncture, 2013
Objectives: This study was designed to investigate the effects of Calculus Bovis-Fel Uris-Moschus pharmacopuncture (BUM) on the regional cerebral blood flow (rCBF) and the mean arterial blood pressure (MABP) in normal and cerebral ischemic rats and to ...
Park Soo-Jung , Lee Ho-Young , Choi Na-Rae , Kwon Young-Mi , Joo Jong-Cheon   +4 more
doaj   +1 more source

Relation of post-stroke headachto cerebrovascular pathology and hemodynamics

Folia Neuropathologica, 2022
Despite high prevalence of cerebrovascular stroke, headache attributed to ischemic strokes is often undertreated and overlooked. The aim is to detect the relation of a post-stroke headache to cerebrovascular pathology and changes in hemodynamics through ...
Elsayed Abed, Nabil Hussein Mohammed, Ahmed Hassan Elsheshiny, Sandra Ahmed, Mohamed Hamed Rashad   +4 more
doaj   +1 more source

Cerebrovascular Variants in Posterior Circulation [PDF]

Circulation Research, 2016
Ever since the identification of hypertension around 150 years ago, researchers have struggled to find its cause(s) with only minor successes.1 Essential, or primary, or idiopathic hypertension is historically defined as a rise in blood pressure (BP) without any known causes, which still accounts for ≈95% of all hypertension.2 Whereas multiple risk ...
Dileep R, Yavagal, Kunakorn, Atchaneeyasakul   +1 more
openaire   +2 more sources

Elastomeric Micro‐Balloons for Remote Control of Cerebral Blood Flow and Real‐Time In vivo Imaging of Rodent Brain Response to Hypoperfusion

Advanced Materials, EarlyView.
This study reports the fabrication of MRI‐compatible elastomeric micro‐balloons via a multi‐step bubble casting process, where the monolithic elastomeric wall is selectively stiffened for reversible and controlled inflation and elasticity, depending on the target vessels for graded occlusion of cerebral arteries.
Jong Bin Kim, Jinghui Wang, Yinding Chi, Jingxian Wu, Alicia Ng, Guanda Qiao, Honglin Tan, Miroslaw Janowski, Piotr Walczak, Yajie Liang, Shu Yang   +10 more
wiley   +1 more source

Additive Manufacturing of Patient‐Specific Intracranial Aneurysm Cell Culture Models

Advanced Materials Technologies, EarlyView.
Patient‐specific intracranial aneurysm models were fabricated using chocolate moulding, 3D printed water‐soluble cores, and direct resin 3D printing. Moulding PDMS around sacrificial cores made of chocolate or 3D printed water‐soluble resin yielded accurate, expandable, and endothelializable models that outperformed resin‐based approaches.
Chloe M. de Nys, Jaimee‐Lee Wood, James I. Novak, Danilo Carluccio, Craig D. Winter, Ashley R. Murphy, Mark C. Allenby   +6 more
wiley   +1 more source

Anticoagulants for acute ischaemic stroke [PDF]

, 2015
Peer reviewedPublisher ...
Counsell, Carl, Kane, Edward J, Sandercock, Peter A G   +2 more
core   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Gestational Hypoxia and Blood-Brain Barrier Permeability: Early Origins of Cerebrovascular Dysfunction Induced by Epigenetic Mechanisms

Frontiers in Physiology, 2021
Fetal chronic hypoxia leads to intrauterine growth restriction (IUGR), which is likely to reduce oxygen delivery to the brain and induce long-term neurological impairments.
Emilio A. Herrera, Alejandro González-Candia   +1 more
doaj   +1 more source

Extracranial-Intracranial Vascular Shunt Procedures [PDF]

, 1976
Cerebrovascular occlusive disease has been and continues to be a leading cause of death and disability throughout the world. In the United States there are about 400,000 new strokes each year. Some 90% of strokes are a result of vascular occlusion of the
Sakalas, Romas
core   +1 more source