Results 91 to 100 of about 9,336,854 (363)

Gompertz Law‐Based Biological Age (GOLD BioAge): A Simple and Practical Measurement of Biological Ageing to Capture Morbidity and Mortality Risks

open access: yesAdvanced Science, EarlyView.
The Gompertz law‐based biological age metric (GOLD BioAge) introduces interpretable convenient and interpretable calculations to capture mortality, disease, and frailty risks. Its applications to proteomics and metabolomics (ProtAge and MetAge) demonstrate clinical potential to enhance aging evaluation and prevent age‐related diseases.
Meng Hao   +14 more
wiley   +1 more source

Nomogram prediction model for the risk of intracranial hemorrhagic transformation after intravenous thrombolysis in patients with acute ischemic stroke

open access: yesFrontiers in Neurology
BackgroundHemorrhagic transformation (HT) after intravenous thrombolysis (IVT) might worsen the clinical outcomes, and a reliable predictive system is needed to identify the risk of hemorrhagic transformation after IVT.MethodsRetrospective collection of ...
Yong Ma   +5 more
doaj   +1 more source

Associations between cerebrovascular risk factors and parkinson disease

open access: yesAnnals of Neurology, 2019
To determine whether cerebrovascular risk factors are associated with subsequent diagnoses of Parkinson disease, and whether these associations are similar in magnitude to those with subsequent diagnoses of Alzheimer disease.
Benjamin R. Kummer   +7 more
semanticscholar   +1 more source

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

open access: yesAdvanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang   +6 more
wiley   +1 more source

A novel cerebrovascular drug-coated balloon catheter for treating symptomatic intracranial atherosclerotic stenosis lesions: Study protocol for a prospective, multicenter, single-arm, target-value clinical trial

open access: yesJournal of Interventional Medicine, 2023
Background: Previous single-center studies have demonstrated that drug-coated balloons (DCBs) may reduce restenosis rates, which is an important factor affecting the prognosis for intracranial interventional therapy.
Qianhao Ding   +12 more
doaj  

Association of Vegetable Nitrate Intake With Carotid Atherosclerosis and Ischemic Cerebrovascular Disease in Older Women

open access: yesStroke, 2017
Background and Purpose— A short-term increase in dietary nitrate (NO3−) improves markers of vascular health via formation of nitric oxide and other bioactive nitrogen oxides.
C. Bondonno   +10 more
semanticscholar   +1 more source

Hyperlipidemia in Cerebrovascular Disease

open access: yesJapanese Circulation Journal, 1975
1. Hypertriglyceridemia and hyper beta-lipoproteinemia are closely related to the pathophysiologic status of the cerebrovascular patients. 2. The electrophoretic analysis of serum lipoprotein is the usefull method for the study on hyperlipidemia in the cerebrovascular disease. 3.
Seitoku Mizuno   +2 more
openaire   +4 more sources

CD74 Blockade Disrupts Endothelial Migrasome Signaling to Prevent Inflammatory Macrophage Differentiation and Inhibit Atherosclerotic Progression

open access: yesAdvanced Science, EarlyView.
Migrasomes play a crucial role in endothelial‐immune interactions in atherosclerosis. This study identifies migrasomes as amplifiers in the inflammatory cascade, driving immune‐metabolic reprogramming via “migrasome‐APP‐CD74” signaling. Blocking CD74 disrupts migrasome‐mediated signaling, attenuating atherosclerosis progression.
Kangnan Zhang   +10 more
wiley   +1 more source

Predictive value of ASTRAL score modified by triglyceride glucose index for prognosis in ischemic stroke

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Objective To investigate the predictive value of a modified Acute Stroke Registry and Analysis of Lausanne (ASTRAL) score, in which the triglyceride glucose (TyG) index replaces the glucose parameter of ASTRAL score, for poor prognosis in ischemic ...
PEI Lu-lu   +5 more
doaj   +1 more source

SOCIETY FOR VASCULAR SURGERY CLINICAL PRACTICE GUIDELINES FOR MANAGEMENT OF EXTRACRANIAL CEREBROVASCULAR DISEASE.

open access: yesJournal of Vascular Surgery, 2021
A. AbuRahma   +11 more
semanticscholar   +1 more source

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