Results 91 to 100 of about 443,889 (360)

A novel cerebrovascular drug-coated balloon catheter for treating symptomatic intracranial atherosclerotic stenosis lesions: Study protocol for a prospective, multicenter, single-arm, target-value clinical trial

open access: yesJournal of Interventional Medicine, 2023
Background: Previous single-center studies have demonstrated that drug-coated balloons (DCBs) may reduce restenosis rates, which is an important factor affecting the prognosis for intracranial interventional therapy.
Qianhao Ding   +12 more
doaj  

The Neuro-Ophthalmology of Cerebrovascular Disease [PDF]

open access: yes, 1974
The neuro-ophthalmology of cerebrovascular disease is a vast plain of neuro-ophthalmic vistas, encompassing virtually all areas of disturbances of the eye-brain mechanism.
Harbison, John W.
core   +1 more source

Association between osteoarthritis and cardiovascular disease: systematic review and meta-analysis [PDF]

open access: yes, 2015
Background: To examine for a possible relationship between osteoarthritis and cardiovascular disease (CVD). Design: A systematic review and meta-analysis Methods: Published and unpublished literature from: MEDLINE, EMBASE, CINAHL, the Cochrane Library ...
Hall, Andrew J.   +4 more
core   +2 more sources

Gompertz Law‐Based Biological Age (GOLD BioAge): A Simple and Practical Measurement of Biological Ageing to Capture Morbidity and Mortality Risks

open access: yesAdvanced Science, EarlyView.
The Gompertz law‐based biological age metric (GOLD BioAge) introduces interpretable convenient and interpretable calculations to capture mortality, disease, and frailty risks. Its applications to proteomics and metabolomics (ProtAge and MetAge) demonstrate clinical potential to enhance aging evaluation and prevent age‐related diseases.
Meng Hao   +14 more
wiley   +1 more source

Nomogram prediction model for the risk of intracranial hemorrhagic transformation after intravenous thrombolysis in patients with acute ischemic stroke

open access: yesFrontiers in Neurology
BackgroundHemorrhagic transformation (HT) after intravenous thrombolysis (IVT) might worsen the clinical outcomes, and a reliable predictive system is needed to identify the risk of hemorrhagic transformation after IVT.MethodsRetrospective collection of ...
Yong Ma   +5 more
doaj   +1 more source

Hyperlipidemia in Cerebrovascular Disease

open access: yesJapanese Circulation Journal, 1975
1. Hypertriglyceridemia and hyper beta-lipoproteinemia are closely related to the pathophysiologic status of the cerebrovascular patients. 2. The electrophoretic analysis of serum lipoprotein is the usefull method for the study on hyperlipidemia in the cerebrovascular disease. 3.
Seitoku Mizuno   +2 more
openaire   +4 more sources

Nonlinear Associations Between Working Hours and Overwork-Related Cerebrovascular and Cardiovascular Diseases (CCVD)

open access: yes, 2018
Long working hours are recognized as a risk factor for cerebrovascular and cardiovascular diseases (CCVD). We investigated the relationship between working hours and different CCVD severity outcomes—death, disability, and illness—across industries in ...
Chien, Lung-Chang   +2 more
core   +1 more source

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

open access: yesAdvanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen   +12 more
wiley   +1 more source

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

open access: yesAdvanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang   +6 more
wiley   +1 more source

Long Non-Coding H19 in Lymphocytes: Prognostic Value in Acute Ischemic Stroke Patients

open access: yesPharmaceuticals
Acute ischemic stroke (AIS) is a cerebrovascular disease that seriously affects the physical and mental health and quality of life of patients. However, there is a lack of reliable prognostic prediction methods.
Liyuan Zhong   +7 more
doaj   +1 more source

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