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Cerebrovascular Disorders: Role of Aging [PDF]

open access: yesJournal of Aging Research, 2012
Therapeutic development for neurological diseases, whether cerebrovascular disease, vascular dementia, or Alzheimer's disease (AD), has been largely unsuccessful. Despite the apparent success of numerous pharmacologic agents in preclinical animal models, few have translated successfully from bench to bedside.
Buga, Ana-Maria   +4 more
core   +8 more sources

Cerebrovascular Disorders [PDF]

open access: yesBMC Cardiovascular Disorders, 2023
AbstractCerebrovascular disorders pose a global health concern. Advances in basic and clinical research, including induced pluripotent stem cell models and multi-omic approaches, have improved our understanding and management of these disorders. However, gaps in our knowledge remain.
Granata, Alessandra   +2 more
openaire   +5 more sources

Cerebrovascular Disorders Complicating Pregnancy [PDF]

open access: greenCONTINUUM: Lifelong Learning in Neurology, 2014
This article discusses the physiologic changes of pregnancy and how they affect risk of ischemic and hemorrhagic stroke and then reviews epidemiology, diagnosis, and treatment of ischemic and hemorrhagic stroke in pregnancy and the puerperium.This article updates our understanding of the relationship of preeclampsia/eclampsia to the posterior ...
Steven K. Feske, Aneesh B. Singhal
europepmc   +5 more sources

Call to Action: SARS-CoV-2 and CerebrovAscular DisordErs (CASCADE) [PDF]

open access: yesJ Stroke Cerebrovasc Dis, 2020
Background and purpose: The novel severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), now named coronavirus disease 2019 (COVID-19), may change the risk of stroke through an enhanced systemic inflammatory response, hypercoagulable state, and ...
Abootalebi, S.   +70 more
core   +2 more sources

Emerging Therapies for Cerebrovascular Disorders [PDF]

open access: bronzeStroke, 2004
New information about therapeutic interventions regarding several important aspects of cerebrovascular disease has appeared recently. This short review will focus on new therapeutic developments concerning the prevention of ischemic stroke, acute ischemic stroke therapy trials, and, lastly, the management of patients with intracranial aneurysms. Great
Antoni Davalos, Marc Fisher
openalex   +8 more sources

Fractional Flow in Cerebrovascular Disorders [PDF]

open access: yesInterventional Neurology, 2012
There is an urgent need for stroke experts to advance the care of their patients, yet current approaches are outmoded and have not been successful. The traditional emphasis on the anatomical identification of disease, using percent luminal stenosis, results in suboptimal identification of lesions likely to produce recurrent ischemia and, consequently ...
Edward Feldmann, David S Liebeskind
openaire   +4 more sources

Cerebrovascular disorders caused by hyperfibrinogenaemia [PDF]

open access: bronzeThe Journal of Physiology, 2016
Key points Hyperfibrinogenaemia (HFg) results in vascular remodelling, and fibrinogen (Fg) and amyloid β (Aβ) complex formation is a hallmark of Alzheimer's disease. However, the interconnection of these effects, their mechanisms and implications in cerebrovascular diseases are not known.
Nino Muradashvili   +4 more
openalex   +4 more sources

Deep-learning-enabled Brain Hemodynamic Mapping Using Resting-state fMRI [PDF]

open access: yesnpj Digital Medicine (2023) 116, 2022
Cerebrovascular disease is a leading cause of death globally. Prevention and early intervention are known to be the most effective forms of its management. Non-invasive imaging methods hold great promises for early stratification, but at present lack the sensitivity for personalized prognosis.
arxiv   +1 more source

Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2 [PDF]

open access: yes, 2020
Background and purpose Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported.
Boon, Paul   +6 more
core   +2 more sources

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