Results 111 to 120 of about 160,931 (269)

Association Between Vascular NOTCH3 Aggregation and Disease Severity in a CADASIL Cohort – Implications for NOTCH3 Variant‐Specific Disease Prediction

open access: yesAnnals of Neurology, EarlyView.
Objective Vascular NOTCH3 protein ectodomain aggregation is a pathological hallmark of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a monogenic small vessel disease typically caused by cysteine‐altering variants in NOTCH3.
Minne N. Cerfontaine   +10 more
wiley   +1 more source

CircUCK2 regulates HECTD1‐mediated endothelial‐mesenchymal transition inhibition by interacting with FUS and protects the blood–brain barrier in ischemic stroke

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 39, Issue 1, Page 40-51, January 2023., 2023
Abstract Ischemic stroke (IS) has become a cerebrovascular disease of widespread concern. Overexpression of circUCK2 alleviates neuronal damage in IS. However, the specific regulatory mechanisms of circUCK2 are not fully understood. In this study, we found that circUCK2 and HECT domain E3 ubiquitin ligase 1 (HECTD1) were downregulated in IS models in ...
Jun‐Hong Zhuang   +8 more
wiley   +1 more source

Assessing Sensitivity of Brain-to-Scalp Blood Flows in Laser Speckle Imaging by Occluding the Superficial Temporal Artery [PDF]

open access: yesarXiv
Cerebral blood flow is a critical metric for cerebrovascular monitoring, with applications in stroke detection, brain injury evaluation, aging, and neurological disorders. Non-invasively measuring cerebral blood dynamics is challenging due to the scalp and skull, which obstruct direct brain access and contain their own blood dynamics that must be ...
arxiv  

Acute cardiovascular effects associated with the use of prescription medications: A Danish nationwide screening study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim This study aims to conduct a hypothesis‐generating screening for acute cardiovascular effects of prescription medications. Methods This Danish nationwide screening study was conducted among incident cases of cardiovascular diseases, including myocardial infarction (MI), ischemic stroke (IS), heart failure (HF), venous thromboembolism (VTE),
Saad Hanif Abbasi   +4 more
wiley   +1 more source

Cerebrovascular disorders associated with agenesis of the internal carotid artery: Findings on digital subtraction angiography. [PDF]

open access: yesFront Surg, 2022
Xu X   +10 more
europepmc   +1 more source

VPBSD:Vessel-Pattern-Based Semi-Supervised Distillation for Efficient 3D Microscopic Cerebrovascular Segmentation [PDF]

open access: yesarXiv
3D microscopic cerebrovascular images are characterized by their high resolution, presenting significant annotation challenges, large data volumes, and intricate variations in detail. Together, these factors make achieving high-quality, efficient whole-brain segmentation particularly demanding.
arxiv  

Vessel Wall MRI: clinical implementation in cerebrovascular disorders-technical aspects. [PDF]

open access: yesRadiol Med, 2022
Cirillo L   +9 more
europepmc   +1 more source

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