Results 121 to 130 of about 3,152,690 (357)

Medications, epilepsy and climate change: Added layers of complexity

British Journal of Clinical Pharmacology, EarlyView.
Climate change—the global crisis with pervasive health impacts—has adverse consequences for people with epilepsy (PWE) who have low quality of life due to poor seizure control, socioeconomic disadvantages and comorbidities. This review focuses on the potential effects of climate change on the pharmacological characteristics of antiseizure medications ...
Medine I. Gulcebi, Seyhmus Gavas, Sanjay M. Sisodiya   +2 more
wiley   +1 more source

Metabolic syndrome and cerebrovascular disorders

Анналы клинической и экспериментальной неврологии, 2017
A combination of a number of risk factors, known as metabolic syndrome (MS), leads to fast progression of vascular diseases and the development of severe complications.
M. M. Tanashyan, S. V. Orlov, R. B. Medvedev, O. V. Lagoda, N. G. Omelchenko, N. A. Glotova   +5 more
doaj   +1 more source

Increased circulating insulin-like growth factor-1 in late-onset Alzheimer's disease [PDF]

, 2007
Background: Insulin-like growth factor (IGF)-1 has been implicated in the pathogenesis of Alzheimer's disease ( AD). Methods: We compared the level of circulating total and bioavailable IGF-1, by simultaneous measurements of IGF-1 and IGF binding ...
Bowie, P.C.W, Grant, P.J, Holmes, J.D, Hooper, N.M, Rice, P.J, Vardy, E.R.L.C   +5 more
core   +1 more source

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

British Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière, Anne Batisse, Nathalie Fouilhé Sam‐Laï, Amélie Daveluy, Christine Fournier‐Choma, Sylvie Deheul, Cécile Chevalier, Clémence Lacroix, Valérie Gibaja, Aurélie Aquizerate, Stéphanie Pain, Emilie Jouanjus, Marie‐Christine Picot, Erika Nogue   +13 more
wiley   +1 more source

Impact of diclofenac risk minimization measures addressing cardiovascular risk on analgesic use in musculoskeletal disorders

British Journal of Clinical Pharmacology, EarlyView.
Aims In 2013, risk minimization measures (RMMs) were introduced in Europe to address the increased cardiovascular risk linked to diclofenac. This study aimed to assess the impact of those RMMs on analgesic use. Methods Primary care data from CPRD GOLD (UK) were used.
Tomas Lasys, Yared Santa‐Ana‐Tellez, Satu J. Siiskonen, Daniala L. Weir, Rolf H. H. Groenwold, Helga Gardarsdottir   +5 more
wiley   +1 more source

CEREBROVASCULAR MORBIDITY, LETHALITY AND MORTALITY IN THE MOSCOW REGION IN 2014

Alʹmanah Kliničeskoj Mediciny, 2016
Background: Cerebrovascular disorders are major contributors into mortality of the population. Annually, more than 14 000 subjects die of cardiovascular disorders in the Moscow Region, 50% of them when being in a hospital.Aim: Informational support of ...
A. N. Gurov, N. A. Katuntseva
doaj   +1 more source

Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders. [PDF]

, 2016
Apolipoprotein (apo) E was initially described as a lipid transport protein and major ligand for low density lipoprotein (LDL) receptors with a role in cholesterol metabolism and cardiovascular disease.
Mahley, Robert W
core   +1 more source

Efficient Extraction of Phenolic Compounds From Cariniana rubra Gardener Ex Miers From the Legal Amazon: Ultrasound‐Assisted Optimization, Chemical Characterization, and Antioxidant Potential

Chemistry &Biodiversity, EarlyView.
ABSTRACT Cariniana rubra, native to the Brazilian Cerrado and the Amazon‐Cerrado ecotone, is traditionally used in folk medicine but remains underexplored. This study optimized extraction yield and bioactive compound content using ultrasound‐assisted extraction (UAE) and Soxhlet extraction.
Aline Biggi Maciel, Elis Ramos de Queiroz Jácome, Naísa Andrade da Silva, Rachel de Moura Nunes Fernandes, Claudia Andrea Lima Cardoso, Elisandra Scapin   +5 more
wiley   +1 more source

Edema progression in proximity to traumatic microbleeds: Evolution of cytotoxic and vasogenic edema on serial MRI

NeuroImage: Reports
Introduction: Although cerebral edema is common following traumatic brain injury (TBI), its formation and progression are poorly understood. This is especially true for the mild TBI population, who rarely undergo magnetic resonance imaging (MRI) studies,
Jacquie Lee, Emily Baniewicz, Nicole L. Peterkin, Danielle Greenman, Allison D. Griffin, Neekita Jikaria, L. Christine Turtzo, Marie Luby, Lawrence L. Latour   +8 more
doaj  

Morphogenetic Variability as Potential Biomarker of Functional Outcome After Ischemic Stroke

Brain Sciences, 2019
The aim of our study was to evaluate the role of morphogenetic variability in functional outcome of patients with ischemic stroke. The prospective study included 140 patients with acute ischemic stroke, all of whom were tested upon: admission; discharge;
Milan Savic, Suzana Cvjeticanin, Milica Lazovic, Ljubica Nikcevic, Ivana Petronic, Dragana Cirovic, Dejan Nikolic   +6 more
doaj   +1 more source