Results 121 to 130 of about 331,793 (319)

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

open access: yesAdvanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Morphogenetic Variability as Potential Biomarker of Functional Outcome After Ischemic Stroke

open access: yesBrain Sciences, 2019
The aim of our study was to evaluate the role of morphogenetic variability in functional outcome of patients with ischemic stroke. The prospective study included 140 patients with acute ischemic stroke, all of whom were tested upon: admission; discharge;
Milan Savic   +6 more
doaj   +1 more source

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

open access: yesAdvanced Science, EarlyView.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song   +9 more
wiley   +1 more source

Ontologies for the study of neurological disease [PDF]

open access: yes, 2012
We have begun work on two separate but related ontologies for the study of neurological diseases. The first, the Neurological Disease Ontology (ND), is intended to provide a set of controlled, logically connected classes to describe the range of ...
Cox, Alexander P.   +7 more
core  

“Time Is Brain” – for Cell Therapies

open access: yesAdvanced Science, EarlyView.
The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin   +4 more
wiley   +1 more source

PSYCHOTHERAPY OF PATIENTS WITH HYPOCHONDRIAC AND OBSESSIVE-COMPULSIVE DISORDERS DUE TO PERINATAL CEREBROVASCULAR LESIONS [PDF]

open access: diamond, 2018
Sergii Boltivets   +4 more
openalex   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

open access: yesAdvanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin   +18 more
wiley   +1 more source

Air Pollution and Cerebrovascular Disorders with Special Reference to Asia: An Overview. [PDF]

open access: yesAnn Indian Acad Neurol, 2022
Taimuri B   +6 more
europepmc   +1 more source

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