Results 131 to 140 of about 160,931 (269)

Laplacian Flow Dynamics on Geometric Graphs for Anatomical Modeling of Cerebrovascular Networks [PDF]

arXiv, 2019
Generating computational anatomical models of cerebrovascular networks is vital for improving clinical practice and understanding brain oxygen transport. This is achieved by extracting graph-based representations based on pre-mapping of vascular structures.
arxiv  

Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature

Neurobiology of Disease, 2018
Background: Cerebrovascular dysfunction and inflammation occur in epilepsy. Here we asked whether pericytes, a pivotal cellular component of brain capillaries, undergo pathological modifications during experimental epileptogenesis and in human epilepsy ...
Wendy Klement, Rita Garbelli, Emma Zub, Laura Rossini, Laura Tassi, Benoit Girard, Marine Blaquiere, Federica Bertaso, Julie Perroy, Frederic de Bock, Nicola Marchi   +10 more
doaj  

Toll-Like Receptor Signaling Pathways: Novel Therapeutic Targets for Cerebrovascular Disorders. [PDF]

Int J Mol Sci, 2021
Ashayeri Ahmadabad R, Mirzaasgari Z, Gorji A, Khaleghi Ghadiri M.   +3 more
europepmc   +1 more source

Efficient Epistemic Uncertainty Estimation in Cerebrovascular Segmentation [PDF]

arXiv
Brain vessel segmentation of MR scans is a critical step in the diagnosis of cerebrovascular diseases. Due to the fine vessel structure, manual vessel segmentation is time consuming. Therefore, automatic deep learning (DL) based segmentation techniques are intensively investigated.
arxiv  

Xixin Decoction May Treat Vascular Dementia by Modulating the NPTX2/C1q/C3 Complement Pathway

Chemistry &Biodiversity, EarlyView.
To establish a VaD model, SD rats underwent unilateral common carotid artery ligation, followed by gavage treatment with Xixin decoction. Cognitive abilities of the rats were assessed through Morris water maze and new object recognition. Pathological changes were observed using electron microscopy observation, Golgi staining, and Nissl staining ...
Shuo Yang, Xin‐qi Gao, Ai‐hua Tan, Pan Ge   +3 more
wiley   +1 more source

Preventive catheter ablation for ventricular arrhythmias in patients with end‐stage heart failure referred for heart transplantation evaluation: Rationale for and design of the CASTLE‐VT trial

European Journal of Heart Failure, EarlyView.
Aims Timely referrals for transplantation and left ventricular assist device (LVAD) play a key role in favourable outcomes in patients with advanced heart failure (HF). Cardiovascular mortality, driven by sudden cardiac death, is the main reason for dying while waiting for heart transplantation (HTx). The purpose of the Preventive Catheter Ablation for
Christian Sohns, Thomas Fink, Harry J.G.M. Crijns, Angelika Costard‐Jaeckle, Nassir F. Marrouche, Samuel Sossalla, Rene Schramm, Mustapha El Hamriti, Maximilian Moersdorf, Maxim Didenko, Martin Braun, Vanessa Sciacca, Frank Konietschke, Volker Rudolph, Jan Gummert, Jan G.P. Tijssen, Philipp Sommer, for the CASTLE‐VT Investigators   +17 more
wiley   +1 more source

FlowMRI-Net: A Generalizable Self-Supervised 4D Flow MRI Reconstruction network [PDF]

arXiv
Background: Image reconstruction from highly undersampled 4D flow MRI data can be very time consuming and may result in significant underestimation of velocities depending on regularization, thereby limiting the applicability of the method. The objective of the present work was to develop a generalizable self-supervised deep learning-based framework ...
arxiv  

Obesity treatment initiation, retention, and outcomes in the Veterans Affairs MOVE! Program among rural and urban veterans

Obesity Science &Practice, Volume 8, Issue 6, Page 784-793, December 2022., 2022
Abstract Objective Rural veterans have high obesity rates. Yet, little is known about this population's engagement with the Veterans Affairs (VA) weight management program (MOVE!). The study objective is to determine whether MOVE! enrollment, anti‐obesity medication use, bariatric surgery use, retention, and outcomes differ by rurality for veterans ...
Kathleen M. Robinson, Mark Vander Weg, Helena H. Laroche, Margaret Carrel, Jason Wachsmuth, Krista Kazembe, Mary Vaughan Sarrazin   +6 more
wiley   +1 more source

Acute Cerebrovascular Disorders and Vasculopathies Associated with Significant Mortality in SARS-CoV-2 Patients Admitted to The Intensive Care Unit in The New York Epicenter. [PDF]

J Stroke Cerebrovasc Dis, 2021
Al-Mufti F, Becker C, Kamal H, Alshammari H, Dodson V, Nuoman R, Dakay K, Cooper J, Gulko E, Kaur G, Sahni R, Scurlock C, Mayer SA, Gandhi CD.   +13 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source