Results 181 to 190 of about 1,666,949 (283)

Maternal and perinatal outcomes associated with prophylactic erythrocytapheresis in pregnant women with sickle cell disease

open access: yes
International Journal of Gynecology &Obstetrics, EarlyView.
Pedro Junqueira Fleury Silva   +12 more
wiley   +1 more source

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song   +7 more
wiley   +1 more source

FOXC1: A Key Transcription Factor of VSMC‐Derived Foam Cell Formation in Atherosclerotic Plaque Instability

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian   +4 more
wiley   +1 more source

Structural Carotid Atherosclerosis and Mild Behavioral Impairment: A Cross‐Sectional Study in a Community‐Dwelling Population

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mild behavioral impairment (MBI) is a late‐life neuropsychiatric syndrome proposed as an early clinical manifestation of neurodegenerative disease. Vascular pathology contributes to late‐life cognitive and behavioral changes; however, its relationship with MBI remains insufficiently characterized.
Po‐Han Chen   +6 more
wiley   +1 more source

Rapid Postmortem Temporal Bone Extraction and Dissection of Human Inner Ear Organs From Organ Donors

open access: yesThe Laryngoscope, EarlyView.
We developed a postmortem protocol for temporal bone extraction and dissection in organ donors, enabling atraumatic bilateral temporal bone retrieval within 1–2 h of ischemia, followed by stepwise microsurgical dissection of neurosensory organs. Combining rapid extraction, abbreviated decalcification, and atraumatic microsurgical dissection, this ...
Yassine Balhi   +10 more
wiley   +1 more source

A Gap Analysis of Deep Brain Stimulation for Childhood‐Onset Movement Disorders

open access: yesMovement Disorders, EarlyView.
Abstract Background Deep brain stimulation (DBS) is an established and increasingly utilized therapy for childhood‐onset movement disorders. However, pediatric DBS poses unique challenges that are not adequately addressed by adult‐derived paradigms. Objective To identify key gaps in the current use of DBS in childhood‐onset movement disorders and to ...
Daniela Munoz‐Chesta   +6 more
wiley   +1 more source

Fifteen‐Year Outcomes of Bilateral Pallidal Stimulation in Isolated Generalized Dystonia: Characterization of Therapeutic Response and Emergence of Parkinsonism

open access: yesMovement Disorders, EarlyView.
Abstract Background Bilateral pallidal deep brain stimulation (GPi‐DBS) is effective for dystonia. Long‐term evolution of therapeutic benefit and emergence of parkinsonism have not been systematically characterized. Objectives To assess 15‐year dystonia outcomes and characterize parkinsonism after bilateral GPi‐DBS.
Clément Desjardins   +51 more
wiley   +1 more source

Lewy Body Disease Across Aging: Clinical and Neuropathological Correlates in a Population Brain Bank

open access: yesMovement Disorders, EarlyView.
Abstract Background Lewy body disease (LBD) is defined by neuronal α‐synuclein pathology, but how Braak‐staged LBD relates to mixed neuropathology and clinical manifestations within a single population‐based cohort remains incompletely characterized. This is especially relevant in cohorts enriched for younger individuals, which may better inform real ...
Vitor Ribeiro Paes   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy