Results 251 to 260 of about 160,931 (269)

Senescent Endothelial Cells in Cerebral Microcirculation Are Key Drivers of Age‐Related Blood–Brain Barrier Disruption, Microvascular Rarefaction, and Neurovascular Coupling Impairment in Mice

Aging Cell, EarlyView.
Senolytic therapy restores neurovascular function, blood–brain barrier integrity, and cognitive performance in aged mice by targeting endothelial senescence. Findings highlight that brain microvascular endothelial cells are highly vulnerable to aging‐induced senescence, and early intervention in middle age may be the most effective strategy to prevent ...
Boglarka Csik, Ádám Nyúl‐Tóth, Rafal Gulej, Roland Patai, Tamas Kiss, Jordan Delfavero, Raghavendra Y. Nagaraja, Priya Balasubramanian, Santny Shanmugarama, Anna Ungvari, Siva Sai Chandragiri, Kiana Vali Kordestan, Mark Nagykaldi, Peter Mukli, Andriy Yabluchanskiy, Sharon Negri, Stefano Tarantini, Shannon Conley, Tae Gyu Oh, Zoltan Ungvari, Anna Csiszar   +20 more
wiley   +1 more source

The conundrum of the connection between severe psychiatric disorders and dementia. [PDF]

Dement Neuropsychol
Teixeira AL, de Erausquin GA, Olvera RL.
europepmc   +1 more source

Acupuncture for somatosensory deficits after stroke: a systematic review and meta-analysis. [PDF]

Front Med (Lausanne)
Ren S, Chen Y, Liu Y, Lv Q, Peng J, Song L, Zou Y, Zhang H, Chen X.   +8 more
europepmc   +1 more source

Cardiovascular Risk Predicts White Matter Hyperintensities, Brain Atrophy and Treatment Resistance in Major Depressive Disorder: Role of Genetic Liability

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Depressive disorders are a leading cause of global disease burden, particularly with the challenge of treatment‐resistant depression (TRD). Research points to a complex bidirectional relationship between cardiovascular (CV) risk factors and TRD, with CV risk negatively impacting brain structure and potentially influencing ...
Marco Paolini, Melania Maccario, Virginia Saredi, Anna Verri, Federico Calesella, Laura Raffaelli, Cristina Lorenzi, Sara Spadini, Raffaella Zanardi, Cristina Colombo, Sara Poletti, Francesco Benedetti   +11 more
wiley   +1 more source

All‐Cause and Cause‐Specific Mortality Among Individuals With Major Depression: A Nationwide Danish Matched‐Cohort Study

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Mental disorders are associated with excess risk of death from unnatural and natural causes, but few studies have differentiated causes of death among patients with major depression. We examined cumulative and relative risks of all‐cause and cause‐specific mortality in individuals with major depression up to 50 years after diagnosis
Merete Osler, Thomas Wolff Rosenqvist, Maarten Pieter Bjørn‐Rozing, Anders Jorgensen, Martin Balslev Jorgensen, Terese Sara Høj Jørgensen, Frederikke Hørdam Gronemann   +6 more
wiley   +1 more source

Analysis of risk factors for depression in peritoneal dialysis patients and establishment of a risk nomogram model. [PDF]

Clinics (Sao Paulo)
Yang M, Tang X, Fang Y.
europepmc   +1 more source

Identifying hazardous alcohol use in primary care using phosphatidylethanol: Timing of screening matters

Addiction, EarlyView.
Abstract Background and Aims Alcohol is a well‐established risk factor for numerous health conditions, making screening for hazardous alcohol use in healthcare a critical task. While self‐reported data suggest that alcohol consumption varies across seasons, this seasonal fluctuation has not yet been confirmed using objective biological markers.
Viktor Månsson, Maria Hårdstedt, Anders Hammarberg, Anders Hake, Riccardo LoMartire   +4 more
wiley   +1 more source

Tactile, thermal and gustatory stimulation therapy in the treatment of post-stroke oropharyngeal dysphagia: a scoping review. [PDF]

Codas
Matos J, Andrade RA, Bilheri DFD, Santos MA, Oliveira DL, Pernambuco LA, Furkim AM.   +6 more
europepmc   +1 more source

Opportunities and Challenges of Population Pharmacogenomics

Annals of Human Genetics, EarlyView.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou, Yoomi Park, Mahamadou D. Camara, Volker M. Lauschke   +3 more
wiley   +1 more source

CADASIL Syndrome Presenting as Obsessive-Compulsive Disorder: A Case Report. [PDF]

Noro Psikiyatr Ars
Canlı D, Keskin M.
europepmc   +1 more source