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Genetics of Cerebrovascular Disorders

Mayo Clinic Proceedings, 2005
Physicians must be able to recognize stroke caused by a mendelian or mitochondrial disorder. Some genetic disorders such as sickle cell anemia and Fabry disease have proven disease-specific treatments, whereas others have no effective treatment, including cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy ...
James F. Meschia   +2 more
openaire   +3 more sources

Stroke and cerebrovascular disorders

Current Opinion in Pediatrics, 2009
Stroke and cerebrovascular disorders in childhood are a cause for significant morbidity in childhood. There is growing emphasis on understanding the mechanisms of stroke so as to inform developments in investigation and management.Advances have been made in the classification of pediatric stroke, aided by clinical and radiological recognition of ...
Nomazulu Dlamini, Fenella J. Kirkham
openaire   +2 more sources

Uric acid in metabolic and cerebrovascular disorders: a review.

Current Vascular Pharmacology, 2019
BACKGROUND Several studies showed a close link between metabolic syndrome (MetS), type 2 diabetes (T2DM) and cerebrovascular diseases. There is considerable debate regarding the role of uric acid (UA) as a risk factor in these conditions. OBJECTIVE The
F. Cortese   +8 more
semanticscholar   +1 more source

Cerebrovascular disorders and genetic polymorphisms: mitochondrial DNA5178C is predominant in cerebrovascular disorders

Journal of the Neurological Sciences, 2002
We studied polymorphisms of mitochondrial DNA 5178cytosine/adenine (mt5178C/A) and angiotensin I-converting enzyme (ACE) genes (DCP1) in 127 cerebrovascular disorder (CVD) patients and 294 age-matched normal controls to clarify the genetic background of Japanese patients with CVD.
Suminori Akiba   +10 more
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Cerebrovascular Disorders in the Prenatal Period

Journal of Child Neurology, 2008
Fetal stroke can occur between the 14th week of pregnancy and the beginning of labor. The incidence is approximately 17-35 of 100 000 live births. Risk factors are correlated to the mother, the pregnancy, or the factors associated with the fetus itself. Computerized tomography and magnetic resonance imaging are the most commonly used imaging techniques.
DICUONZO, Franca   +6 more
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Cerebrovascular disorders in children

Current Neurology and Neuroscience Reports, 2004
Cerebrovascular disorders are an important cause of mortality and chronic morbidity in children. International incidence rates for childhood stroke (ie, from 30 days to 18 years of age) have ranged from 1.3 to 13 per 100,000 children. Ischemic stroke is probably more common than hemorrhagic stroke in children.
openaire   +3 more sources

Pediatric Cerebrovascular Disorders [PDF]

open access: possibleMayo Clinic Proceedings, 1989
This monograph is the first of its kind devoted entirely to cerebrovascular disorders in infants and children. Early in the text, the authors contrast the diversity of cerebrovascular conditions in children with adults. Accordingly, the text includes both an etiologic approach to diagnosis as well as management issues.
openaire   +3 more sources

Cerebrovascular Disease and Disorders

2010
Cerebrovascular diseases are a common cause of cognitive impairment in adults and a clinically significant cause of cognitive disability in children. Ischemic and hemorrhagic stroke are the main types of cerebrovascular disease. Risk factors for stroke, clinical signs and symptoms, diagnostic evaluation and treatment are discussed for each category of ...
Nancy Minniti   +2 more
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Antiplatelet Therapy in Cerebrovascular Disorders

2012
Antiplatelet treatment is a mainstay in acute and long-term secondary stroke prevention. Aspirin is still most widely used worldwide, however, there is increasing evidence from small randomised trials that dual antiplatelet therapy combining aspirin with dipyridamole or clopidogrel might be more effective in the acute and early chronic post-ischemic ...
Weber, Ralph   +2 more
openaire   +4 more sources

Cerebrovascular disorders in childhood

2013
Cerebrovascular problems in childhood include diverse problems of vascular supply to the brain and occur with an overall frequency of from 5 to 8/100000 children/year. Signs and symptoms at manifestation are manifold. They depend not only on localization of the infarction but also on age at injury and specific risk factors.
openaire   +3 more sources

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