Results 31 to 40 of about 248,312 (241)

Reorganization of the Brain Structural Covariance Network in Ischemic Moyamoya Disease Revealed by Graph Theoretical Analysis

Frontiers in Aging Neuroscience, 2022
ObjectiveIschemic moyamoya (MMD) disease could alter the cerebral structure, but little is known about the topological organization of the structural covariance network (SCN).
Peijing Wang, Peijing Wang, Peijing Wang, Peijing Wang, Wenjie Li, Wenjie Li, Wenjie Li, Wenjie Li, Huan Zhu, Huan Zhu, Huan Zhu, Huan Zhu, Xingju Liu, Xingju Liu, Xingju Liu, Xingju Liu, Tao Yu, Tao Yu, Tao Yu, Tao Yu, Dong Zhang, Dong Zhang, Dong Zhang, Dong Zhang, Yan Zhang, Yan Zhang, Yan Zhang, Yan Zhang   +27 more
doaj   +1 more source

The collaterome: A novel conceptual framework of systems biology in cerebrovascular disorders

Brain Circulation, 2015
The collaterome is the elaborate neurovascular architecture within the brain that regulates and determines the compensatory ability, response, and outcome of cerebrovascular pathophysiology.
David S Liebeskind
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Hyperemia detection on arterial spin labeling is associated with final infarct volume in stroke post-endovascular therapy

Journal of Stroke and Cerebrovascular Diseases
Background and Purpose: Patients with acute ischemic stroke (AIS) treated with endovascular therapy (EVT) may develop hyperemia due to loss of relative cerebral blood flow (rCBF) autoregulation.
Carolyn A. Lomahan, BS, Marie Luby, PhD, Georgios Kalarakis, MD, PhD, Amie W. Hsia, MD, John K. Lynch, DO, MPH, Karan P. Nathani, MD, Sana Somani, MD, Leila C. Thomas, BSN, MPH, Fabian Arnberg-Sandor, MD, PhD, Lawrence L. Latour, PhD   +9 more
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CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Concurrency of Early-Age Exposure to Chinese Famine and Diabetes Increases Recurrence of Ischemic Stroke

Frontiers in Neurology, 2021
Background and Purpose: Early age exposure to the Chinese Great Leap Forward famine (1959–1961) is associated with the incidence of risk factors for ischemic stroke.
Yue Suo, Yue Suo, Yue Suo, Yue Suo, Weiqi Chen, Weiqi Chen, Weiqi Chen, Weiqi Chen, Yuesong Pan, Yuesong Pan, Yuesong Pan, Yuesong Pan, Hao Li, Hao Li, Hao Li, Hao Li, Xia Meng, Xia Meng, Xia Meng, Xia Meng, Zixiao Li, Zixiao Li, Zixiao Li, Zixiao Li, Chunjuan Wang, Chunjuan Wang, Chunjuan Wang, Chunjuan Wang, Jing Jing, Jing Jing, Jing Jing, Jing Jing, Yilong Wang, Yilong Wang, Yilong Wang, Yilong Wang, Yongjun Wang, Yongjun Wang, Yongjun Wang, Yongjun Wang   +39 more
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Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

Triglyceride Glucose Index and Prognosis of Patients With Ischemic Stroke

Frontiers in Neurology, 2020
Background: The triglyceride glucose index (TyG index) has been proposed as a simple and credible surrogate marker of insulin resistance. However, it is unclear whether TyG index correlates with adverse clinical outcomes in patients with ischemic stroke.
Yimo Zhou, Yimo Zhou, Yimo Zhou, Yimo Zhou, Yuesong Pan, Yuesong Pan, Yuesong Pan, Yuesong Pan, Hongyi Yan, Hongyi Yan, Hongyi Yan, Hongyi Yan, Yilong Wang, Yilong Wang, Yilong Wang, Yilong Wang, Zixiao Li, Zixiao Li, Zixiao Li, Zixiao Li, Xingquan Zhao, Xingquan Zhao, Xingquan Zhao, Xingquan Zhao, Hao Li, Hao Li, Hao Li, Hao Li, Xia Meng, Xia Meng, Xia Meng, Xia Meng, Chunxue Wang, Chunxue Wang, Chunxue Wang, Chunxue Wang, Liping Liu, Liping Liu, Liping Liu, Liping Liu, Yongjun Wang, Yongjun Wang, Yongjun Wang, Yongjun Wang   +43 more
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Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Time-dependent changes of autophagy and apoptosis in lipopolysaccharide-induced rat acute lung injury [PDF]

Iranian Journal of Basic Medical Sciences, 2016
Objective(s): Abnormal lung cell death including autophagy and apoptosis is the central feature in acute lung injury (ALI). To identify the cellular mechanisms and the chronology by which different types of lung cell death are activated during ...
Li Lin, Lijun Zhang, Liangzhu Yu, Lu Han, Wanli Ji, Hui Shen, Zhenwu Hu   +6 more
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