Results 121 to 130 of about 2,687 (277)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Gift-giving, Quasi-Credit and Reciprocity [PDF]
The fluctuations in incomes inherent in rural communities can be attenuated by reciprocal assistance. A model of reciprocal assistance based upon rational action and voluntary participation is presented.
Tim Worrall, Jonathan P. Thomas
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Intelligence in Media and Public Participation: Analysis and Implications
In the emerging era of technology, social media is an important part of everyday life. However, if not properly directed, it can have negative impacts. Emotional skills are essential for positive social media behavior.
Solviana, Meita Dwi +3 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
THE REACTION OF MEMBERS OF THE CORVIDAE TO THE DEATH OF AN INDIVIDUALS OF THEIR SPECIES
, 2022 Було помічено, що європейська сорока (Pica pica) реагує на мертвих особин свого виду скупченням та какофонією. Біля особини, яку вбив яструб-тетеревятник (Accipiter gentilis), зібралося від 10 до 15 сорок. Описані різні види реагування на загиблих особин
Брезгунова, О. О.
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The Theory of Institutional Change Revisited: The Institutional Dichotomy, Its Dynamic, and Policy Implications in a More Formal Analysis [PDF]
, 2011 The original institutionalist theory of institutional change as elaborated by Paul D. Bush (1987) in the traditions of Veblen, Ayres and J.F. Foster (called here the VAFB-paradigm), provides a most important theoretical and empirical device for critical ...
Elsner, Wolfram
core
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Ritual Culture is The Main Phenomenon Formation of Intercultural Communication
, 2021 The article examines the main approaches of ritual culture, which reveal the definition of the concept of ritual culture as a phenomenon of the spiritual life of the people. Ritual culture is the main part in the life of the people. Formation of the rule
Menlimuratova Elmira Azatovna
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