Results 121 to 130 of about 59,022 (277)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Folkecology and commons management in the Maya Lowlands [PDF]
Three groups living off the same rainforest habitat manifest strikingly distinct behaviors, cognitions, and social relationships relative to the forest.
Douglas Medin +6 more
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Staging Memories at the Narayanhiti Palace Museum, Kathmandu [PDF]
, 2017 This article focuses on a particular time (present-day Nepal, post-monarchy) and site (the Narayanhiti Palace Museum) that offers a compelling space for understanding the negotiation of the country’s recent past, revealing much about the transition from ...
Whitmarsh, Bryony R
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Spartan Daily, March 23, 1976 [PDF]
, 1976 Volume 66, Issue 31https://scholarworks.sjsu.edu/spartandaily/6062/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The Pipe Site, a Late Caddo Site at Lake Palestine in Anderson County, Texas [PDF]
, 2011 Buddy Calvin Jones excavated a Late Caddo cemetery and midden site he called the Lake Palestine site, in Anderson County, Texas, in March 1968. His notes indicate that a total of 21 Caddo burials were excavated at the site, and the burials were situated ...
Perttula, Timothy K.
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Control and change studying the process of institutionalisation [PDF]
This paper studies the process by which a change in the institutional logic of an organisational field diffuses through the management control system of a firm.change; institutionalisation; management control systems; decoupling ...
Dambrin, Claire +2 more
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