Results 231 to 240 of about 2,687 (277)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

The legacy of colonialism and commercial tobacco-caused social inequities. [PDF]

J Natl Cancer Inst Monogr
Fagan P, Alexander LA.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Psychoactive and other ceremonial plants from a 2,000-year-old Maya ritual deposit at Yaxnohcah, Mexico. [PDF]

PLoS One
Lentz DL, Hamilton TL, Meyers SA, Dunning NP, Reese-Taylor K, Hernández AA, Walker DS, Tepe EJ, Esquivel AF, Weiss AA.   +9 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

A Call To Reinforce One Health Preparedness in Response To the Global Re-emergence of Anthrax. [PDF]

J Epidemiol Glob Health
Al-Tawfiq JA, Memish ZA.
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Prevalence, types, and demographic characteristics associated with major life changes following psychedelic use. [PDF]

Sci Rep
Carlisle NA, Simonsson O, MacCarthy S, Elliott MN, Miller GH, Goldberg SB, Shallcross RA, Hendricks PS.   +7 more
europepmc   +1 more source

Access to land and nature as health determinants: a qualitative analysis exploring meaningful human-nature relationships among Indigenous youth in central Canada. [PDF]

BMC Public Health
Hatala AR, Morton D, Deschenes C, Bird-Naytowhow K.   +3 more
europepmc   +1 more source

A cultural memory semiotics and function behavior structure model for digital inheritance and innovation in AI generated Huizhou woodcarving images. [PDF]

Sci Rep
Qian Y, Bao Q, Zhang S, Peng X.
europepmc   +1 more source