Runoff Potential Index (RPI): 3D modelling of surface-driven hydrological dynamics for drought resilience. [PDF]
Sci RepCorrea ES.
europepmc +1 more source
Interventions for children with developmental coordination disorder: A scoping review
Developmental Medicine &Child Neurology, EarlyView.This scoping review identified 13 differing categories of interventions delivered to children with developmental coordination disorder worldwide ranging from task oriented, motor skills training, and sensorimotor approaches to sports training approaches and health promotion, with motor performance mostly reported as outcome and similar effectiveness ...
Dorothee Jelsma +9 more
wiley +1 more source
Individualism and working from home
Economic Inquiry, EarlyView.Abstract We show that culturally transmitted individualism is an important determinant of working from home (WFH). Using individual‐level data from the U.S. Current Population Survey (CPS) and the European Social Survey (ESS), we compare immigrants and their descendants from different cultural backgrounds residing in the same location.
Jan Bietenbeck +2 more
wiley +1 more source
Glucosuria as a Biomarker of Adherence to Sodium-Glucose Co-Transporter Protein Type 2 Inhibitors. [PDF]
Patient Prefer AdherenceEscribano-Serrano J +8 more
europepmc +1 more source
Economics &Politics, EarlyView.ABSTRACT The electoral effects of natural disasters have gained increasing importance in recent research. This paper analyzes the impact of an unprecedentedly strong tornado on the electoral results of coalition government parties in the 2021 Czech general election.
Jakub Jusko, Peter Spáč
wiley +1 more source
Identification of cancer mini-drivers by deciphering selective landscape in the cancer genome. [PDF]
Brief BioinformZhu X +9 more
europepmc +1 more source
The FEBS Journal, EarlyView.Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal +8 more
wiley +1 more source
Lock, relax, load, and shoot: a molecular perspective on Nedd4 regulation
The FEBS Journal, EarlyView.Structural basis of inactive and active states of the Nedd4 HECT E3 ligase subfamily, following a ‘lock, relax, load, and shoot’ mechanism. In the locked, autoinhibited state, intramolecular domain interactions restrain the HECT domain. Relaxation releases these restraints, allowing loading of ubiquitin onto the catalytic cysteine, followed by the ...
Masa Janosev +2 more
wiley +1 more source
Assessment and mapping of climate change impacts on spring wheat yield in Southern Saskatchewan using DSSAT and high-resolution RCM projections. [PDF]
Sci RepZare M, Azam S, Sauchyn D, Yaghoubi F.
europepmc +1 more source
Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases
The FEBS Journal, EarlyView.Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek +12 more
wiley +1 more source