Results 211 to 220 of about 368,885 (312)

Maintaining Paediatric Resuscitation Readiness: A Clinical Teacher's Toolbox for Low-Dose, High-Frequency Practice. [PDF]

Clin Teach
Lilitwat W.
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Direct Certification With Medicaid and School Lunch Participation Among Maryland Public Schools.

JAMA Netw Open
Hatton CR, Dou N, Gross J, Arbaiza R, Hager ER, Gross SM.   +5 more
europepmc   +1 more source

Ethical and regulatory aspects of facial scanning in dentistry: a scoping review. [PDF]

Clin Oral Investig
Jindanil T, Lahoud P, Ducret M, Richert R, Wagner JK, Jacobs R.   +5 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Proficiency in Robotic Cardiac Surgery: Toward a Brazilian Training Curriculum. [PDF]

Braz J Cardiovasc Surg
Poffo R, Curcio SAF, Rosado ADR, Senna S, Pope RB, Toschi AP.   +5 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Neurodegenerative Disease Death Certification Among National Football League Players With Dementia.

JAMA Netw Open
Luster CB, Nowinski CJ, Abdolmohammadi B, Feigel ED, Mastrodicasa MJ, Finegan B, Goldstein L, Katz DI, Cantu RC, Dwyer B, Tripodis Y, Stein TD, Alosco ML, McKee AC, Mez J, Daneshvar DH.   +15 more
europepmc   +1 more source

Biorisk Management in High-Containment Laboratories: Assessment of Certification Systems and Need for Global Standardization. [PDF]

Pathogens
Garbuglia AR, Zulian V, Pauciullo S, Lapa D.   +3 more
europepmc   +1 more source