Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Regulation of laboratory-developed tests and in-house in vitro diagnostic medical devices in the United States and the European Union-a comparative overview. [PDF]
Kahles A +13 more
europepmc +1 more source
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley +1 more source
A secured accreditation and equivalency certification using Merkle mountain range and transformer based deep learning model for the education ecosystem. [PDF]
Krishnan S, Rajendran S, Zakariah M.
europepmc +1 more source
Geographical Distance, Socioeconomic Deprivation, and Educational Level Shape Access to Voluntary Termination of Pregnancy in a Southern Region of Italy. [PDF]
Bartolomeo N +4 more
europepmc +1 more source
Global landscape and professionalization of infection preventionist education: comparative insights and future directions. [PDF]
Cao YL +8 more
europepmc +1 more source
A Comparative Analysis of Risk-Based Food Safety Inspection Methods Across EU Countries and Canada. [PDF]
Ze Y +3 more
europepmc +1 more source
The future of Italian phase I trials regulation: lessons from a nationwide survey. [PDF]
Cagnazzo C +8 more
europepmc +1 more source

