Results 81 to 90 of about 57,965 (266)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effect of Supplementary Cementitious Materials on Post-fire Performance of Concrete Columns

International Journal of Concrete Structures and Materials
This study evaluates the material behavior of heated concrete with varying supplementary cementitious material (SCM) contents and quantifies its effect on the post-fire performance of reinforced concrete (RC) columns. The novelty of this research lies in
Yeokyeong Lee, Yeonju Chun, Venkatesh Kodur, Hee Sun Kim   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Local certification of unitary operations

Scientific Reports
In this work, we analyze the local certification of unitary quantum channels, which is a natural extension of quantum hypothesis testing. A particular case of a quantum channel operating on two systems corresponding to product states at the input, is ...
Ryszard Kukulski, Mateusz Stępniak, Kamil Hendzel, Łukasz Pawela, Bartłomiej Gardas, Zbigniew Puchała   +5 more
doaj   +1 more source

Analysis of International Service Standards of International Patient Management

Здоровье мегаполиса
Background. The article is the first to analyze international certification systems for medical tourism as key drivers for growing export of medical services while healthcare is getting international and Russian medical advances are introduced to the ...
E. V. Chernyshev, G. D. Petrova
doaj   +1 more source

Concurrent Treatment With Lorlatinib and Dinutuximab Beta Induced Acute Gastric Dilation in a Pediatric Patient With Neuroblastoma

Pediatric Blood &Cancer, EarlyView.
Suna Lin, Linjie Li, JiJun Chen, Zhaokun Tao, Lifeng Zhang, Junqing Mao, Jinhu Wang   +6 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Sustainable agriculture made easy: CETARA-NF's self-certification

Journal of Agriculture and Food Research
Consumers can receive guarantees through the certified evaluation tool of agriculture resources analysis of natural farming (CETARA NF) without having to deal with costly third-party certification's entry obstacles or complex participatory guarantee ...
Rohit Kumar Vashishat, Subhash Sharma, Rajeshwar Singh Chandel, Inder Dev, Gaurav Singh Chauhan, Divyanshu, Ashish Gupta, Manoj Gupta, Chinglembi Laishram   +8 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source