Results 61 to 70 of about 653 (260)

Ownership balance, supervisory efficiency of independent directors and the quality of management earnings forecasts

open access: yesChina Journal of Accounting Research, 2013
In the Chinese securities market, with its characteristics of influence through personal relationships (Guanxi) and underdeveloped standards of law and enforcement, can independent directors play the supervisory role expected by securities regulators? In
Yunling Song   +2 more
doaj   +1 more source

Machine Learning‐Enhanced Ultrasensitive Immuno‐CRISPR Array Facilitates Early Diagnosis of Alzheimer's Disease by Detecting Multiple Plasma Biomarkers

open access: yesAdvanced Science, EarlyView.
This work presents a CRISPR‐based, ultrasensitive multiplex protein detection array capable of simultaneously analyzing six plasma biomarkers associated with Alzheimer's disease (AD). By integrating antibody‐mediated signal transduction, recombinase polymerase amplification, and spatially encoded CRISPR‐Cas12a, the system achieves detection sensitivity
Liding Zhang   +9 more
wiley   +1 more source

The challenges of competency based education of Certified Public Accountant

open access: yesContabilidad y Negocios: Revista del Departamento Académico de Ciencias Administrativas, 2013
The interest of this paper is based on presenting the importance of educational instruction today, in general and in particular the accounting career. This, it should be noted, is part of the development trends of cognitive skills, instrumental skills ...
José Carlos Dextre Flores
doaj  

Mock board examination results as predictors in the Licensure Examination for Certified Public Accountants

open access: yesJournal of Global Education and Research
This study was conducted to determine whether the mock board examination performance can predict a candidate’s performance in the Licensure Examination for Certified Public Accountants (LECPA).
Yzekeil Camacho   +5 more
doaj   +1 more source

Unconstrained Coordination of Pt Single Atoms on Distorted g‐C3N4 Enables Electronic Flexibility and Enhanced Microplastics Photoreforming

open access: yesAdvanced Science, EarlyView.
This study reveals Pt single atoms anchored on distorted graphitic carbon nitride, exhibiting flexible coordination and enhanced interfacial charge transfer. Combined spectroscopy and DFT reveal asymmetric Pt─N environments that promote photoreforming of microplastics into hydrogen, demonstrating a solar‐driven pathway for plastic upcycling with ...
Ting‐Han Lin   +9 more
wiley   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan   +11 more
wiley   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

open access: yesAdvanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu   +9 more
wiley   +1 more source

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

open access: yesAdvanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta   +10 more
wiley   +1 more source

Influence of the Certified Public Accountant Licensure Examination on Accounting Students’ Attitudes

open access: yesInternational Journal of Multidisciplinary: Applied Business and Education Research
This research explores the influence of the Certified Public Accountant Licensure Examination (CPALE) on the attitudes and readiness of accountancy students, aiming to improve program outcomes and board examination results. The study surveyed predominantly female respondents aged 19-29, with a monthly family income below 9,520 and a general weighted ...
Aniceto, Maybel Joy A.   +3 more
openaire   +2 more sources

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

open access: yesAdvanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo   +27 more
wiley   +1 more source

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