Results 231 to 240 of about 663,705 (337)

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon   +21 more
wiley   +1 more source

Discovering Interpretable Semantics from Radio Signals for Contactless Cardiac Monitoring

open access: yesAdvanced Science, EarlyView.
This study presents a semantic representation framework for clinically interpretable cardiac monitoring from contactless radio signals. It formulates radio semantic learning as an information‐bottleneck problem and approximates the objective via intra‐modal compression and cross‐modal alignment, structuring radio measurements into meaningful semantic ...
Jinbo Chen   +10 more
wiley   +1 more source

Fixed‐Linkage Enabled Ultra‐Stable Ion Transport Channels in Membranes for Long‐Life Alkaline Flow Batteries

open access: yesAdvanced Science, EarlyView.
Rigid fixed‐ethylene‐linked PBI membrane stabilizes ion‐transport channels, enabling high ionic conductivity and durable alkaline Zn─Fe flow batteries. ABSTRACT Alkaline zinc–iron redox flow batteries (Zn─Fe FBs) are promising candidates for developing high‐voltage and cost‐effective grid‐scale energy storage systems.
Zhiquan Wei   +14 more
wiley   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon   +20 more
wiley   +1 more source

Engineered Interfacial Control for Suppression of Phase Instability: Operando Visualization from Device to Module Scale

open access: yesAdvanced Science, EarlyView.
Operando real‐time current density–voltage absorption spectroscopy visualizes spatial phase evolution in mixed‐halide perovskites from device to module scale. Phase instability preferentially initiates in regions with insufficient carrier extraction, revealing electrical boundary conditions as governing factors.
Hangyeol Choi   +8 more
wiley   +1 more source

Tracing the Dynamic Chemical Transformations of Spiro‐OMeTAD in Operating Perovskite Solar Cells

open access: yesAdvanced Science, EarlyView.
Mapping of Spiro‐OMeTAD layer's chemistry and electronic properties in PSC: Advanced cluster ion‐beam sputtering depth profile XPS reveals that environmental stressors (light, potential, and moisture) trigger the decomposition of LiTFSI dopants in Spiro‐OMeTAD.
Chittaranjan Das   +6 more
wiley   +1 more source

Electrostatic Potential Complementarity for Thickness‐Tolerant Cathode Interlayers in High‐Efficiency Organic and Tandem Solar Cells

open access: yesAdvanced Science, EarlyView.
Two model molecules — trimesic acid (TMA) and phloroglucinol (PG) — with opposite central electrostatic potential (ESP) distributions are employed to elucidate how molecular electrostatic interactions regulate the cathode interlayer (CIL) PDINN. Electrostatic potential complementarity is revealed as the intrinsic origin of thickness sensitivity in CILs,
Xiaoman Ding   +13 more
wiley   +1 more source

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