Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy
Advanced Materials, EarlyView.Weakly assembled peptide amphiphile nanostructures disassemble in circulation and reassemble with blood biomolecules, mainly lipoproteins. Binding to blood biomolecules prolongs blood circulation and improves accumulation in solid tumors. In the tumor microenvironment, peptide amphiphiles assemble with cholesterol‐rich domains of cell membranes ...
Li Xiang +19 more
wiley +1 more source
Pattern of cervical lymph node metastases from papillary carcinoma of the thyroid [PDF]
, 2001 Ranjiv Sivanandan, Khee Chee Soo
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Advanced Materials, EarlyView.Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno +15 more
wiley +1 more source
Machine learning-based screening and validation of pyroptosis-associated prognostic genes and potential drugs in cervical cancer. [PDF]
BMC Med GenomicsHou Z, Tang G, Chu H, Wang Z, Wang L.
europepmc +1 more source
Quantitative Diffusion and Perfusion MRI as Response Predictor in Cervical Squamous Cell Carcinoma Treated with CCRT [PDF]
Rajat Nandi +4 more
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Advanced Materials, EarlyView.This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding +11 more
wiley +1 more source
Does age affect surgical outcomes in patients with degenerative cervical myelopathy? Results from the prospective multicenter AOSpine International study on 479 patients [PDF]
, 2015 Hiroaki Nakashima +10 more
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Advanced Materials, EarlyView.This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba +20 more
wiley +1 more source
CT Hounsfield units in cervical ossification of the posterior longitudinal ligament-A comparison with other forms of degenerative cervical myelopathy using propensity score matching. [PDF]
BMC Musculoskelet DisordGuo K, Xia Y, Zong Y, Yu Y.
europepmc +1 more source