Results 181 to 190 of about 708,585 (354)
It is shown that hepatic c‐Fos responds to feeding, altering de novo lipogenesis, glycolysis, and a wide range of steatosis‐associated metabolic signaling pathways. Obesogenic diets cause hepatic c‐Fos overexpression, insulin resistance, and the induction of metabolic reprogramming‐related genes.
Ao Li +8 more
wiley +1 more source
This study identifies ADP‐ribosylation factor‐like protein 3 (ARL3) as a novel chaperone that stabilizes estrogen receptor α (ERα) in breast cancer. ARL3 promotes tumor growth by recruiting USP10 to remove ubiquitin chains from ERα, preventing its degradation.
Han Li +14 more
wiley +1 more source
Epidemiology of cervical cancer
Cervical cancer is the fifth most common cancer in European women. The recognition of a viral agent such as Human Papillomavirus (HPV) as a necessary cause in the development of cervical cancer implies that this disease may be prevented by effective prophylactic or therapeutic interventions against this infection.
Alves, Carla, Alves, Luís, Lunet, Nuno
openaire +2 more sources
COP9 signalosome subunit 6 (CSN6) promotes the auto‐ubiquitination and degradation of DDB1‐CUL4 associated factor 1 (DCAF1), thereby antagonizing DCAF1‐mediated ubiquitination of Nucleophosmin (NPM1). This stabilization of NPM1 enhances the ribosome biogenesis process and the translation of specific gemcitabine‐resistance proteins, ultimately driving ...
Yijing Zhang +14 more
wiley +1 more source
Cervical cancer screening policies and implementation in Uganda - a qualitative study on policymakers', cervical cancer experts' and gynecologists' perspectives. [PDF]
De Paepe E +4 more
europepmc +1 more source
LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Association Between Age and Race and Cervical Cancer Stage. [PDF]
Santos N +7 more
europepmc +1 more source

