Results 191 to 200 of about 708,585 (354)
Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama +17 more
wiley +1 more source
Cytological Classification Diagnosis for Thyroid Nodules via Multimodal Model Deep Learning
This study introduces AI‐TFNA, an innovative artificial intelligence model designed to assist cytopathologists in classifying thyroid nodules based on The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). The model effectively differentiates between benign and malignant thyroid nodules, demonstrating significant potential as a screening ...
Yuanzheng Lou +27 more
wiley +1 more source
Determinants of delay in presentation to completion of treatment in cervical cancer. [PDF]
Begum D +10 more
europepmc +1 more source
This study identifies the unconventional role of CXCL2 in regulating neutrophil polarization and immune responses in HCC. Unlike the common view that CXCL2 acts mainly as an extracellular chemokine, intracellular CXCL2 can interact with YBX1 and prevent its nuclear translocation.
Xin Liu +13 more
wiley +1 more source
Molecular Screening for Cervical Cancer. [PDF]
Martins TR, Levi JE.
europepmc +1 more source
Acute myeloid leukemia (AML) remains a therapeutic challenge due to its heterogeneity and limited targets. Here, multi‐omics analyses are utilized, and it is revealed that AML cells, particularly the FLT3‐ITD+ subtype, undergo chaperone‐mediated ER stress, inducing surface translocation of ER chaperones.
Yimin Zhou +13 more
wiley +1 more source
HPV-Independent Cervical Cancer-A New Challenge of Modern Oncology. [PDF]
Hurjui RM +5 more
europepmc +1 more source
ITM2B Truncation Promotes Migrasome Formation to Accelerate Renal Cell Carcinoma Growth
This study identifies truncated ITM2B as a regulator of migrasome formation in renal cell carcinoma (RCC) cells. The ITM2B truncation not only facilitates migrasome formation by recruiting TSPAN4, but also sorts active caspase‐7 into migrasomes. The internalization of active caspase‐7‐enriched migrasomes by macrophages stimulates IL‐6 secretion to ...
Qi‐tao Chen +10 more
wiley +1 more source

