Results 181 to 190 of about 513,529 (353)

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Interventions in Primary Care to Improve Cervical Cancer Screening: A Systematic Review. [PDF]

Cureus
Ahmed AE, Hatan WM, Alrehaili SE, Alghamdi WR, Altarif HK, Alotaibi GS, Alkhamis HY, Alfaya RF, Mejamemi HA, Aljasas HI.   +9 more
europepmc   +1 more source

Addressing Underscreening for Cervical Cancer among South Asian Women: Using Concept Mapping to Compare Service Provider and Service User Perspectives of Cervical Screening in Ontario, Canada [PDF]

Kimberly Devotta, Patricia O’Campo, Jacqueline L. Bender, Aïsha Lofters   +3 more
openalex   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Integrating Biomarkers into Cervical Cancer Screening-Advances in Diagnosis and Risk Prediction: A Narrative Review. [PDF]

Diagnostics (Basel)
Gisca T, Matasariu DR, Ursache A, Socolov DG, Scripcariu IS, Fudulu A, Anton ET, Botezatu A.   +7 more
europepmc   +1 more source

ATTITUDE OF FEMALE STUDENTS IN PUBLIC TERTIARY INSTITUTION IN IMO ABOUT CERVICAL CANCER SCREENING

Chinyere Emmanuela Ngumah, Jerome O. Okafor   +1 more
openalex   +1 more source

NIR Ratiometric Fluorescent Antibody‐Drug Conjugate for Metastatic Ovarian Cancer Theranostics and Treatment Response Monitoring

Advanced Science, EarlyView.
In vivo optical imaging enhances antibody‐drug conjugate (ADC) optimization by enabling real‐time monitoring of stimulus‐responsive drug behavior. We report n501‐CYMMAF, a ratiometric theranostic with strong target affinity and low‐dose efficacy for ovarian metastasis.
Cheng Li, Zezhong Yu, Tao Pu, Yanling Wu, Gang Wang, Youhua Xie, Tianlei Ying, Zhenlin Yang, Yibing Shi   +8 more
wiley   +1 more source

Impact of replacing cytology with human papillomavirus testing for cervical cancer screening on the prevalence of Trichomonas vaginalis: a modelling study [PDF]

, 2018
Ben B. Hui, Caitlin P Reulein, Rebecca Guy, Basil Donovan, Jane S. Hocking, Matthew Law, David G. Regan   +6 more
openalex   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Factors Associated With Low Utilization of Cervical Cancer Screening Services in Gazipur, Bangladesh. [PDF]

Obstet Gynecol Int
Kabir SF, Ashik-Ur-Rahman M, Rahman A, Hossen MA, Rahman R, Huq F, Haque M, Marfi JF, Khan MAS, Hawlader MDH.   +9 more
europepmc   +1 more source