Results 21 to 30 of about 31,741 (238)

Immunohistochemical Expression of NQO1 in Premalignant Lesions and Squamous Cell Carcinoma of Cervix and its Correlation with Histopatholigic Factors [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2022
Introduction: Cervical cancer is one of the most important malignancies in women which has a unique progression due to premalignant lesions. The present study was performed with aim to evaluate the expression of NQO1 protein in patients with premalignant
Amir Hossein Jafarian, Nema Mohamadian Roshan, Masoumeh Gharib, Hasan Mehrad-Majd, Asma Ahrari Roudi   +4 more
doaj   +1 more source

HPV IMMUNOHISTOCHEMICAL TESTING AND CERVICAL DYSPLASIA [PDF]

Medicine and Pharmacy Reports, 2016
Background and aim. HPV (Human Papilloma Virus) infection represents a necessary condition for cervical carcinogenesis. The purpose of this study was to evaluate the efficiency of HPV testing using an immunohistochemical staining kit with implications upon both diagnosis and treatment of cervical intraepithelial neoplasia (CIN).Methods.
MUREŞAN, DANIEL, ROTAR, IOANA CRISTINA, APOSTOL, SILVANA, COROIU, GEORGIANA, STAMATIAN, FLORIN   +4 more
openaire   +2 more sources

Socioclinical risk factors for cervical dysplasia and presence of human papillomavirus among women attending a tertiary care teaching hospital of Central Odisha

Indian Journal of Community and Family Medicine
Introduction: Carcinoma cervix being the second-most common gynecological malignancy in India contributes nearly 14% of all cancers in females. Cervical dysplasia and presence of human papillomavirus (HPV) DNA are the two most important factors for ...
Swetaleena Ashe, Saumya Nanda, Roma Rattan, Tapas Ranjan Behera   +3 more
doaj   +1 more source

A rare case of cervical dysplasia

Journal of Obstetrics and Gynaecology, 2019
A 15-year-old patient presented with primary amenorrhoea, cyclical lower abdominal pain and persistent backache for three years.
Sarmed Sami, Khunda, Taghreed, Hmod, Rasha, Abbas, Aethele, Khunda   +3 more
openaire   +2 more sources

Reliability of the CINtecTM p16INK4a immunocytochemical test in screening cervical precancerous lesions [PDF]

Vojnosanitetski Pregled, 2008
Background/Aim. Overexpression of p16INK4a has been found to be linked with genomic integration of high-risk human papillomavirus (HPV) and the developement of precancerous cervical intraepithelial lesions. The aim of this study was to examine is there a
Jović Milena, Nenadić Dane, Magić Zvonko, Zoltarevski Lidija, Đurđević-Vukomanović Biserka, Tatomirović Željka, Strelić Nataša, Vojvodić Danilo   +7 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

The relationship between staffing of the obstetrics and gynecology service and indicators of detection of cervical dysplasia in Ukraine

Український журнал Перинатологія і педіатрія
Cervical dysplasia is one of the leading precancerous pathologies of the female reproductive system and an important marker of the effectiveness of cervical cancer prevention.
P.Yu. Tokar
doaj   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

The Homozygous p.(Arg215Ter) Variant in XRCC2 Is Associated With Atypical Fanconi Anemia Without Major Hematological Abnormalities in Childhood

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Fanconi Anemia (FA) is the most frequent inherited bone marrow failure syndrome. A role for the XRCC2 gene in FA was suspected in 2012 and confirmed in 2016, but only two affected individuals have been described thus far, and no long‐term follow‐up is available.
Sabina Cenciarelli, Giulia Bruna Marchetti, Maria Iascone, Maria Grazia Patricelli, Sara Giangiobbe, Gabriella Cinzia Pozzobon, Miriam Nella Savini, Fabio Giglio, Alessandro Aiuti, Paola Carrera, Francesca Ferrua, Angela Peron   +11 more
wiley   +1 more source

Development of a 3D in vitro human-sized model of cervical dysplasia to evaluate the delivery of ethyl cellulose-ethanol injection

Frontiers in Biomaterials Science
Introduction: Cervical cancer, the second leading cause of cancer-related death for women worldwide, remains a preventable yet persistent disease that disproportionately affects women in low and middle-income countries (LMICs).
Ines A. Cadena, Gatha Adhikari, Alyssa Almer, Molly Jenne, Ndubuisi Obasi, Nicolas F. Soria Zurita, Willie E. Rochefort, Jenna L. Mueller, Jenna L. Mueller, Jenna L. Mueller, Kaitlin C. Fogg   +10 more
doaj   +1 more source